Literature DB >> 10986089

Approaches to the fully functionalized DEF ring system of ristocetin A via highly selective ruthenium-promoted S(N)Ar reaction.

A J Pearson1, J N Heo.   

Abstract

Ruthenium-promoted intramolecular S(N)Ar reaction has allowed the construction of the fully functionalized 16-membered DEF macrocycle 4 of ristocetin A that incorporates the required arylglycine and arylserine residues as the F and E ring, respectively.

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Year:  2000        PMID： 10986089     DOI： 10.1021/ol000180h

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Studies toward the total synthesis of ristocetin A aglycone using arene-ruthenium complexes as S(N)Ar substrates: Construction of an advanced tricyclic intermediate.

Authors:  Anthony J Pearson; Diana V Ciurea; Avdhoot Velankar
Journal:  Tetrahedron Lett       Date:  2008-03-17       Impact factor: 2.415

2.  Tetrafluoropyridyl (TFP): a general phenol protecting group readily cleaved under mild conditions.

Authors:  William D G Brittain; Steven L Cobb
Journal:  Org Biomol Chem       Date:  2019-02-20       Impact factor: 3.876
  2 in total

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