Literature DB >> 10986086

Catalytic asymmetric conjugate addition of nitroalkanes to cycloalkenones.

S Hanessian1, V Pham.   

Abstract

Nitroalkanes add to cyclic and acyclic enones in an enantioselective manner in the presence of catalytic quantities of L-proline and trans-2,5-dimethylpiperazine as excess additive.

Entities:  

Year:  2000        PMID： 10986086     DOI： 10.1021/ol000170g

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Identification, Synthesis, and Characterization of a Major Circulating Human Metabolite of TRPV4 Antagonist GSK2798745.

Authors:  Joseph E Pero; John J McAtee; David J Behm; Jacques Briand; Grazyna Graczyk-Millbrandt; Karl Erhard; Andrew D Roberts; Ralph A Rivero; Dennis A Holt; Brian G Lawhorn
Journal:  ACS Med Chem Lett       Date:  2021-08-30       Impact factor: 4.632

2.  Rate limiting step precedes C-C bond formation in the archetypical proline-catalyzed intramolecular aldol reaction.

Authors:  Hui Zhu; Fernando R Clemente; K N Houk; Matthew P Meyer
Journal:  J Am Chem Soc       Date:  2009-02-11       Impact factor: 15.419

Review 3.  Synergistic Strategies in Aminocatalysis.

Authors:  Antonio Del Vecchio; Arianna Sinibaldi; Valeria Nori; Giuliana Giorgianni; Graziano Di Carmine; Fabio Pesciaioli
Journal:  Chemistry       Date:  2022-07-04       Impact factor: 5.020
  3 in total

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