H K Kang1, C M Mahan, K Y Lee, C A Magee, S H Mather, G Matanoski. 1. Environmental Epidemiology Service, Veterans Health Administration Department of Veterans Affairs, Washington, DC 20036-3406, USA. han.kang@mail.va.gov
Abstract
BACKGROUND: Since the 1965-1975 Vietnam War, there has been persistent concern that women who served in the U.S. military in Vietnam may have experienced adverse pregnancy outcomes. METHODS: We compared self-reported pregnancy outcomes for 4,140 women Vietnam veterans with those of 4,140 contemporary women veterans who were not deployed to Vietnam. As a measure of association, we calculated odds ratios (OR) and 95% confidence intervals (CI) using logistic regression adjusting for age at conception, race, education, military nursing status, smoking, drinking and other exposures during pregnancy. RESULTS: There was no statistically significant association between military service in Vietnam and index pregnancies resulting in miscarriage or stillbirth, low birth weight, pre-term delivery, or infant death. The risk of having children with "moderate-to-severe" birth defects was significantly elevated among Vietnam veterans (adjusted OR = 1.46, 95% CI = 1.06-2.02). CONCLUSIONS: The risk of birth defects among index children was significantly associated with mother's military service in Vietnam.
BACKGROUND: Since the 1965-1975 Vietnam War, there has been persistent concern that women who served in the U.S. military in Vietnam may have experienced adverse pregnancy outcomes. METHODS: We compared self-reported pregnancy outcomes for 4,140 women Vietnam veterans with those of 4,140 contemporary women veterans who were not deployed to Vietnam. As a measure of association, we calculated odds ratios (OR) and 95% confidence intervals (CI) using logistic regression adjusting for age at conception, race, education, military nursing status, smoking, drinking and other exposures during pregnancy. RESULTS: There was no statistically significant association between military service in Vietnam and index pregnancies resulting in miscarriage or stillbirth, low birth weight, pre-term delivery, or infantdeath. The risk of having children with "moderate-to-severe" birth defects was significantly elevated among Vietnam veterans (adjusted OR = 1.46, 95% CI = 1.06-2.02). CONCLUSIONS: The risk of birth defects among index children was significantly associated with mother's military service in Vietnam.
Authors: Elizabeth M Yano; Lori A Bastian; Susan M Frayne; Alexandra L Howell; Linda R Lipson; Geraldine McGlynn; Paula P Schnurr; Margaret R Seaver; Ann M Spungen; Stephan D Fihn Journal: J Gen Intern Med Date: 2006-03 Impact factor: 5.128
Authors: Timothy S Wells; Linda Z Wang; Christina N Spooner; Tyler C Smith; Katia M Hiliopoulos; Deborah R Kamens; Gregory C Gray; Paul A Sato Journal: Matern Child Health J Date: 2006-07-11
Authors: Kathryn Magruder; Tracey Serpi; Rachel Kimerling; Amy M Kilbourne; Joseph F Collins; Yasmin Cypel; Susan M Frayne; Joan Furey; Grant D Huang; Theresa Gleason; Matthew J Reinhard; Avron Spiro; Han Kang Journal: JAMA Psychiatry Date: 2015-11 Impact factor: 21.596