Literature DB >> 1098117

Effect of the antiepileptic drug sodium valproate on induction of hepatic microsomal P450.

N Sapeika, E R Kaplan.   

Abstract

Sodium valproate is an anticonvulsant which, unlike phenobarbitone, does not produce an increase in rat hepatic P450 when given in large nontherapeutic doses.

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Year:  1975        PMID： 1098117

Source DB:  PubMed          Journal:  Res Commun Chem Pathol Pharmacol        ISSN： 0034-5164


  3 in total

1.  Changes in the concentration of serum alpha 1-acid glycoprotein in epileptic patients.

Authors:  K Morita; A Yamaji
Journal:  Eur J Clin Pharmacol       Date:  1994       Impact factor: 2.953

Review 2.  Drug interactions with valproic acid.

Authors:  R H Levy; K M Koch
Journal:  Drugs       Date:  1982-12       Impact factor: 9.546

3.  Effects of valproate on xenobiotic biotransformation in rat liver. In vivo and in vitro experiments.

Authors:  V Rogiers; A Callaerts; A Vercruysse; M Akrawi; E Shephard; I Phillips
Journal:  Pharm Weekbl Sci       Date:  1992-06-19
  3 in total

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