| Literature DB >> 10980435 |
Abstract
Both flies and mammals remodel the architecture of the X chromosome to achieve dosage compensation. A novel class of noncoding RNAs that paint entire chromosomes are centrally involved in this process. The genes encoding these unusual RNAs are themselves located on the X, and are key sites that target the X for dosage compensation.Mesh:
Substances:
Year: 2000 PMID: 10980435 DOI: 10.1016/s0959-437x(00)00127-1
Source DB: PubMed Journal: Curr Opin Genet Dev ISSN: 0959-437X Impact factor: 5.578