Literature DB >> 10978732

Synthesis of 7alpha-hydroxy derivatives of regulatory oxysterols.

D Li1, T A Spencer.   

Abstract

7alpha-Hydroxy derivatives of oxysterols are of considerable interest because of their possible involvement in regulation of cholesterol metabolism. This paper describes stereoselective syntheses and complete characterization of the 7alpha-hydroxy derivatives of four key oxysterols: 25-hydroxycholesterol, 27-hydroxycholesterol, 24(S)-hydroxycholesterol, and 24(S), 25-epoxycholesterol.

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Year:  2000        PMID： 10978732     DOI： 10.1016/s0039-128x(00)00131-8

Source DB:  PubMed          Journal:  Steroids        ISSN： 0039-128X            Impact factor:   2.668


  3 in total

1.  Oxysterols direct B-cell migration through EBI2.

Authors:  Changlu Liu; Xia V Yang; Jiejun Wu; Chester Kuei; Neelakandha S Mani; Li Zhang; Jingxue Yu; Steven W Sutton; Ning Qin; Homayon Banie; Lars Karlsson; Siquan Sun; Timothy W Lovenberg
Journal:  Nature       Date:  2011-07-27       Impact factor: 49.962

2.  Optimal TBHP allylic oxidation of Delta5-steroids catalyzed by dirhodium caprolactamate.

Authors:  Hojae Choi; Michael P Doyle
Journal:  Org Lett       Date:  2007-11-21       Impact factor: 6.005

3.  Oxysterols direct immune cell migration via EBI2.

Authors:  Sébastien Hannedouche; Juan Zhang; Tangsheng Yi; Weijun Shen; Deborah Nguyen; João P Pereira; Danilo Guerini; Birgit U Baumgarten; Silvio Roggo; Ben Wen; Richard Knochenmuss; Sophie Noël; Francois Gessier; Lisa M Kelly; Mirka Vanek; Stephane Laurent; Inga Preuss; Charlotte Miault; Isabelle Christen; Ratna Karuna; Wei Li; Dong-In Koo; Thomas Suply; Christian Schmedt; Eric C Peters; Rocco Falchetto; Andreas Katopodis; Carsten Spanka; Marie-Odile Roy; Michel Detheux; Yu Alice Chen; Peter G Schultz; Charles Y Cho; Klaus Seuwen; Jason G Cyster; Andreas W Sailer
Journal:  Nature       Date:  2011-07-27       Impact factor: 49.962
  3 in total

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