Literature DB >> 10977922

Peculiarities of cardiotropic effect of aconitine.

Y R Sheikh-Zade1, I L Cherednik, P A Galenko-Yaroshevskii.   

Abstract

In experiments on anesthetized cats, aconitine produced direct arrhythmogenic and cardiotoxic effects on the myocardium combined with indirect cardiotropic effects mediated via activation of extracardial nerves. Aconitine demonstrated pronounced cholinolytic properties and blocked vagal arrhythmogenic effect.

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Year:  2000        PMID： 10977922     DOI： 10.1007/BF02439272

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  4 in total

1.  Quantification of Lappaconitine in Mouse Blood by UPLC-MS/MS and Its Application to a Pharmacokinetic Study.

Authors:  Fan Chen; Xiuwei Shen; Peng Huang; Huiyan Fu; Yue Jin; Congcong Wen
Journal:  Biomed Res Int       Date:  2019-01-06       Impact factor: 3.411

2.  An Intentional Aconite Overdose: A Case Report.

Authors:  Christopher Wood; James Coulson; John Thompson; Stephen Bonner
Journal:  J Crit Care Med (Targu Mures)       Date:  2020-05-06

3.  Toxic Constituents Index: A Toxicity-Calibrated Quantitative Evaluation Approach for the Precise Toxicity Prediction of the Hypertoxic Phytomedicine-Aconite.

Authors:  Ding-Kun Zhang; Rui-Sheng Li; Xue Han; Chun-Yu Li; Zhi-Hao Zhao; Hai-Zhu Zhang; Ming Yang; Jia-Bo Wang; Xiao-He Xiao
Journal:  Front Pharmacol       Date:  2016-06-17       Impact factor: 5.810

Review 4.  The toxicology and detoxification of Aconitum: traditional and modern views.

Authors:  Yau-Tuen Chan; Ning Wang; Yibin Feng
Journal:  Chin Med       Date:  2021-07-27       Impact factor: 5.455
  4 in total

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