| Literature DB >> 1097693 |
G H Fisher, H R Moreno, J E Oatis, H P Schultz.
Abstract
Two series of 2,3-disubstituted 5,8-dimethoxy-6-[N- (omega-dimethylaminoalkyl) amino] quinoxalines were prepared: the first series with identical 2,3-substituents H, CH3, C6H5, C6H4-4-Cl, and CH2C6H5; and the second with identical styryl groups CH=CHC6H5, CH=CHC6H4-4-Cl, CH=CHC6H3-3,4-C12, CH=CHC6H4-4-F, CH=CHC6H4-4-CF3, and CH=CHC6H4-4-NO2. None of the substances possessed antimalarial activity; several were toxic at highest dosage levels.Entities:
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Year: 1975 PMID: 1097693 DOI: 10.1021/jm00241a021
Source DB: PubMed Journal: J Med Chem ISSN: 0022-2623 Impact factor: 7.446