Literature DB >> 10976577

3D QSAR studies on new piperazine derivatives with antihistamine and antibradykinin effects.

H Y Choo1, B J Chung.   

Abstract

Three dimensional QSAR studies for antihistamine and antibradykinin effects of new piper azine derivatives were conducted using the comparative molecular field analysis. Electro static and steric factors, but not hydrophobic factor, of the synthesized compounds were correlated with the antagonistic effect.

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Year:  2000        PMID： 10976577     DOI： 10.1007/BF02975441

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  1 in total

1.  Synthesis and characterization of a disubstituted piperazine derivative with T-type channel blocking action and analgesic properties.

Authors:  Zubaidha Pudukulatham; Fang-Xiong Zhang; Vinicius M Gadotti; Said M'Dahoma; Prabhuling Swami; Yasinalli Tamboli; Gerald W Zamponi
Journal:  Mol Pain       Date:  2016-04-06       Impact factor: 3.395
  1 in total

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