Literature DB >> 10973467

Prevalence of CagA and VacA antibodies in children with Helicobacter pylori-associated peptic ulcer compared to prevalence in pediatric patients with active or nonactive chronic gastritis.

T Alarcón1, M J Martínez, P Urruzuno, M L Cilleruelo, D Madruga, M Sebastian, D Domingo, J C Sanz, M López-Brea.   

Abstract

VacA and CagA serological responses were detected in pediatric patients: 44 and 56%, respectively, in peptic ulcer (PU) patients, 33.3 and 44.4% in active chronic gastritis (ACG) patients, and 23.2 and 39.2% in non-ACG patients. Higher seroprevalence to CagA+VacA and to CagA+VacA+35-kDa antigen was found among PU patients. However, a low level of sensitivity and specificity was found for indirect detection of PU patients.

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Year:  2000        PMID： 10973467      PMCID： PMC95968          DOI： 10.1128/CDLI.7.5.842-844.2000

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN： 1071-412X


  18 in total

1.  cagA and vacA status of Spanish Helicobacter pylori clinical isolates.

Authors:  D Domingo; T Alarcón; N Prieto; I Sánchez; M López-Brea
Journal:  J Clin Microbiol       Date:  1999-06       Impact factor: 5.948

2.  Gastric inflammation is enhanced in children with CagA-positive Helicobacter pylori infection.

Authors:  K L Kolho; R Karttunen; P Heikkilä; H Lindahl; H Rautelin
Journal:  Pediatr Infect Dis J       Date:  1999-04       Impact factor: 2.129

3.  CagA antibodies in Japanese children with nodular gastritis or peptic ulcer disease.

Authors:  S Kato; T Sugiyama; M Kudo; K Ohnuma; K Ozawa; K Iinuma; M Asaka; M J Blaser
Journal:  J Clin Microbiol       Date:  2000-01       Impact factor: 5.948

4.  PCR-based diagnosis of Helicobacter pylori infection in Polish children and adults.

Authors:  A Gzyl; D Dzierzanowska; E Rozynek; D Celinska-Cedro; W Dura; D E Berg
Journal:  J Med Microbiol       Date:  1999-04       Impact factor: 2.472

5.  cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors.

Authors:  S Censini; C Lange; Z Xiang; J E Crabtree; P Ghiara; M Borodovsky; R Rappuoli; A Covacci
Journal:  Proc Natl Acad Sci U S A       Date:  1996-12-10       Impact factor: 11.205

Review 6.  The incidence of Helicobacter pylori infection.

Authors:  J Parsonnet
Journal:  Aliment Pharmacol Ther       Date:  1995       Impact factor: 8.171

7.  Equally high prevalences of infection with cagA-positive Helicobacter pylori in Chinese patients with peptic ulcer disease and those with chronic gastritis-associated dyspepsia.

Authors:  Z J Pan; R W van der Hulst; M Feller; S D Xiao; G N Tytgat; J Dankert; A van der Ende
Journal:  J Clin Microbiol       Date:  1997-06       Impact factor: 5.948

8.  Testing for serum IgG antibodies to Helicobacter pylori cytotoxin-associated protein detects children with higher grades of gastric inflammation.

Authors:  F Luzza; A Contaldo; M Imeneo; M Mancuso; L Pensabene; L Giancotti; A M La Vecchia; M C Costa; P Strisciuglio; C Docimo; F Pallone; S Guandalini
Journal:  J Pediatr Gastroenterol Nutr       Date:  1999-09       Impact factor: 2.839

9.  Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin.

Authors:  Z Xiang; S Censini; P F Bayeli; J L Telford; N Figura; R Rappuoli; A Covacci
Journal:  Infect Immun       Date:  1995-01       Impact factor: 3.441

10.  Importance in diagnosis of gastritis of detection by PCR of the cagA gene in Helicobacter pylori strains isolated from children.

Authors:  M O Husson; F Gottrand; A Vachee; L Dhaenens; E M de la Salle; D Turck; M Houcke; H Leclerc
Journal:  J Clin Microbiol       Date:  1995-12       Impact factor: 5.948
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  3 in total

1.  Comparison of cytotoxin genotypes of Helicobacter pylori in stomach and saliva.

Authors:  Jie Wang; David S Chi; John J Laffan; Chuanfu Li; Donald A Ferguson; Peter Litchfield; Eapen Thomas
Journal:  Dig Dis Sci       Date:  2002-08       Impact factor: 3.199

2.  In situ expression of cagA and risk of gastroduodenal disease in Helicobacter pylori-infected children.

Authors:  James R Rick; Matthew Goldman; Cristina Semino-Mora; Hui Liu; Cara Olsen; Eugenia Rueda-Pedraza; Carolyn Sullivan; Andre Dubois
Journal:  J Pediatr Gastroenterol Nutr       Date:  2010-02       Impact factor: 2.839

3.  Helicobacter pylori Infection among Patients with Dyspepsia and Intrafamilial Transmission.

Authors:  Mustafa Yalçin; Ayla Yalçin; Göksel Bengi; Selim G Nak
Journal:  Euroasian J Hepatogastroenterol       Date:  2016-12-01
  3 in total

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