Literature DB >> 10973074

Mutants yield a pharmacophore model for the tubulin-paclitaxel binding site.

B W Day1.   

Abstract

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Year:  2000        PMID： 10973074     DOI： 10.1016/s0165-6147(00)01521-2

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN： 0165-6147            Impact factor:   14.819


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  3 in total

1.  Characterizing the Epothilone Binding Site on β-Tubulin by Photoaffinity Labeling: Identification of β-Tubulin Peptides TARGSQQY and TSRGSQQY as Targets of an Epothilone Photoprobe for Polymerized Tubulin.

Authors:  Adwait R Ranade; LeeAnn Higgins; Todd W Markowski; Nicole Glaser; Dmitry Kashin; Ruoli Bai; Kwon Ho Hong; Ernest Hamel; Gerhard Höfle; Gunda I Georg
Journal:  J Med Chem       Date:  2016-03-17       Impact factor: 7.446

2.  Pharmacodynamics (PD) and pharmacokinetics (PK) of E7389 (eribulin, halichondrin B analog) during a phase I trial in patients with advanced solid tumors: a California Cancer Consortium trial.

Authors:  Robert J Morgan; Timothy W Synold; Jeffrey A Longmate; David I Quinn; David Gandara; Heinz-Josef Lenz; Christopher Ruel; Bixin Xi; Michael D Lewis; A Dimitrios Colevas; James Doroshow; Edward M Newman
Journal:  Cancer Chemother Pharmacol       Date:  2015-09-11       Impact factor: 3.333

3.  De(side chain) model of epothilone: bioconformer interconversions DFT study.

Authors:  Danuta Rusinska-Roszak; Marek Lozynski
Journal:  J Mol Model       Date:  2009-01-20       Impact factor: 1.810
  3 in total

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