| Literature DB >> 10973066 |
Abstract
The genes that drive heart-cell differentiation in vertebrates and Drosophila are similar, even though the Drosophila 'heart' is a simple tube and the vertebrate heart is a multichambered physiologically complex organ. Mutational analysis in mice and, as particular focus of this review, in zebrafish, reveals the additional genes brought into play to fashion these evolutionarily 'new' organotypic components.Entities:
Mesh:
Year: 2000 PMID: 10973066 DOI: 10.1016/s0168-9525(00)02075-8
Source DB: PubMed Journal: Trends Genet ISSN: 0168-9525 Impact factor: 11.639