Literature DB >> 1097195

Preliminary clinical experience with meptazinol, a new analgesic.

W Oosterlinck, W De Sy.   

Abstract

The analgesic effect of intravenous meptazinol at various dosage levels was studied in 30 patients suffering from acute renal colic. Out of a total of 41 injections (dose range: 20 to 120 mg.) a favourable analgesic response was recorded on 39 occasions. The onset of action was rapid with the minimun duration of action of 1 hour. Higher doses increased the drug's action but were accompanied by nausea and dizziness. There was no overall effect on blood pressure or heart rate.

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Year:  1975        PMID: 1097195     DOI: 10.1185/03007997509113669

Source DB:  PubMed          Journal:  Curr Med Res Opin        ISSN: 0300-7995            Impact factor:   2.580


  3 in total

1.  Studies on the metabolism of meptazinol, a new analgesic drug.

Authors:  R A Franklin; A Aldridge
Journal:  Br J Clin Pharmacol       Date:  1976-06       Impact factor: 4.335

2.  Studies on the absorption and disposition of meptazinol following rectal administration.

Authors:  R A Franklin; P J Southgate; A J Coleman
Journal:  Br J Clin Pharmacol       Date:  1977-04       Impact factor: 4.335

Review 3.  Meptazinol. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy.

Authors:  B Holmes; A Ward
Journal:  Drugs       Date:  1985-10       Impact factor: 9.546

  3 in total

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