Literature DB >> 10970054

Genetic epidemiology of Alzheimer's disease.

J F Dartigues1, L Letenneur.   

Abstract

The genetics of Alzheimer's disease is one of the most complex topics to study from an epidemiological point of view, particularly in population-based studies on polymorphisms of genes. The present review focuses primarily on some conflicting results on genetic epidemiology of Alzheimer's disease, and the major difficulties met in such studies.

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Year:  2000        PMID： 10970054     DOI： 10.1097/00019052-200008000-00004

Source DB:  PubMed          Journal:  Curr Opin Neurol        ISSN： 1350-7540            Impact factor:   5.710


  4 in total

1.  Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.

Authors:  E Kojro; G Gimpl; S Lammich; W Marz; F Fahrenholz
Journal:  Proc Natl Acad Sci U S A       Date:  2001-04-17       Impact factor: 11.205

2.  The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study.

Authors:  Jean-Charles Lambert; Kristel Sleegers; Antonio González-Pérez; Martin Ingelsson; Gary W Beecham; Mikko Hiltunen; Onofre Combarros; Maria J Bullido; Nathalie Brouwers; Karolien Bettens; Claudine Berr; Florence Pasquier; Florence Richard; Steven T Dekosky; Didier Hannequin; Jonathan L Haines; Gloria Tognoni; Nathalie Fiévet; Jean-François Dartigues; Christophe Tzourio; Sebastiaan Engelborghs; Beatrice Arosio; Elicer Coto; Peter De Deyn; Maria Del Zompo; Ignacio Mateo; Merce Boada; Carmen Antunez; Jesus Lopez-Arrieta; Jacques Epelbaum; Brit-Maren Michaud Schjeide; Ana Frank-Garcia; Vilmentas Giedraitis; Seppo Helisalmi; Elisa Porcellini; Alberto Pilotto; Paola Forti; Raffaele Ferri; Marc Delepine; Diana Zelenika; Mark Lathrop; Elio Scarpini; Gabriele Siciliano; Vincenzo Solfrizzi; Sandro Sorbi; Gianfranco Spalletta; Giovanni Ravaglia; Fernando Valdivieso; Saila Vepsäläinen; Victoria Alvarez; Paolo Bosco; Michelangelo Mancuso; Francesco Panza; Benedetta Nacmias; Paola Bossù; Olivier Hanon; Paola Piccardi; Giorgio Annoni; David Mann; Philippe Marambaud; Davide Seripa; Daniela Galimberti; Rudolph E Tanzi; Lars Bertram; Corinne Lendon; Lars Lannfelt; Federico Licastro; Dominique Campion; Margaret A Pericak-Vance; Hilkka Soininen; Christine Van Broeckhoven; Annick Alpérovitch; Agustin Ruiz; M Ilyas Kamboh; Philippe Amouyel
Journal:  J Alzheimers Dis       Date:  2010       Impact factor: 4.472

Review 3.  Concepts for the treatment of Alzheimer's disease: molecular mechanisms and clinical application.

Authors:  Claus Pietrzik; Christian Behl
Journal:  Int J Exp Pathol       Date:  2005-06       Impact factor: 1.925

Review 4.  Genetics of the dementias.

Authors:  J M Schott; N C Fox; M N Rossor
Journal:  J Neurol Neurosurg Psychiatry       Date:  2002-12       Impact factor: 10.154
  4 in total

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