Literature DB >> 10969971

The total synthesis of piclavines A1-4 and their biological evaluation.

H Takahata1, N Okamoto.   

Abstract

The total synthesis of piclavines A1, A2, A3, and A4 has been achieved starting from compound 10 with enantiomeric enhancement. Their biological activities (antibacterial, antimicrobacterial, and antiviral activities and inhibition of cell growth) were evaluated.

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Year:  2000        PMID: 10969971     DOI: 10.1016/s0960-894x(00)00341-3

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  An asymmetric synthesis of all stereoisomers of piclavines A1-4 using an iterative asymmetric dihydroxylation.

Authors:  Yukako Saito; Naoki Okamoto; Hiroki Takahata
Journal:  Beilstein J Org Chem       Date:  2007-10-29       Impact factor: 2.883

  1 in total

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