Literature DB >> 1096975

Selective IgA deficiency---some perspectives.

S Horowitz, R Hong.   

Abstract

The clinical spectrum of IgA deficiency varies from good health to respiratory, gastrointestinal, autoimmune and malignant disorders. Evaluation of B lymphocytes with surface IgA receptors in this disease reveals cap formation, decreased to normal density of IgA receptors, and IgA secretion following pokeweed stimulation. Further study of antigen-induced B-lymphocyte phenomena is needed. The presence of decreased numbers of T-cell markers in some individuals with IgA deficiency suggests a T-"helper" cell defect.

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Year:  1975        PMID: 1096975

Source DB:  PubMed          Journal:  Birth Defects Orig Artic Ser        ISSN: 0547-6844


  5 in total

1.  Circulating immune complexes in IgA deficiency.

Authors:  A O Kwitko; P E McKenzie; D J Shearman; A A Gormly; A J Woodroffe
Journal:  Clin Exp Immunol       Date:  1979-10       Impact factor: 4.330

2.  Genetic linkage of IgA deficiency to the major histocompatibility complex: evidence for allele segregation distortion, parent-of-origin penetrance differences, and the role of anti-IgA antibodies in disease predisposition.

Authors:  I Vorechovský; A D Webster; A Plebani; L Hammarström
Journal:  Am J Hum Genet       Date:  1999-04       Impact factor: 11.025

3.  Immunodeficiency in epilepsy: a new view.

Authors:  A Fontana; P J Grob
Journal:  J Neurol       Date:  1979-01-05       Impact factor: 4.849

4.  IgM and IgD concentrations in the serum and secretions of children with selective IgA deficiency.

Authors:  A Plebani; E Mira; E Mevio; V Monafo; L D Notarangelo; A Avanzini; A G Ugazio
Journal:  Clin Exp Immunol       Date:  1983-09       Impact factor: 4.330

5.  Effect of acute cytomegalovirus infection on drug-induced SLE.

Authors:  A Schattner; Z Sthoeger; D Geltner
Journal:  Postgrad Med J       Date:  1994-10       Impact factor: 2.401

  5 in total

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