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Literature DB >> 1096918

Mechanism of action of extradural analgesia.

Abstract

The factors governing the spread and site of action of local anaesthetics in the extradural space are discussed. Local anaesthetic drugs injected into the extradural space may cause nerve blocks at three possible sites: (a) On the spinal nerves in the paravertebral space. This probably occurs only in young subjects. (b) On the spinal nerves intradurally. This is probably the essential site of blockade. (c) On the spinal cord.

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Year: 1975 PMID： 1096918

Source DB: PubMed Journal: Br J Anaesth ISSN： 0007-0912 Impact factor: 9.166

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Cited

13 in total

1. The effect of age on the systemic absorption, disposition and pharmacodynamics of bupivacaine after epidural administration.

Authors: B T Veering; A G Burm; A A Vletter; R P van den Heuvel; W Onkenhout; J Spierdijk
Journal: Clin Pharmacokinet Date: 1992-01 Impact factor: 6.447

2. Somatosensory feedback from the limbs exerts inhibitory influences on central neural drive during whole body endurance exercise.

Authors: Markus Amann; Lester T Proctor; Joshua J Sebranek; Marlowe W Eldridge; David F Pegelow; Jerome A Dempsey
Journal: J Appl Physiol (1985) Date: 2008-09-11

10. Contribution of Low-Dose Computerized Tomography With Digital Multiplanar Reconstructions in Thoracic Epidurography and Correlation With Sensory Block in Postoperative Analgesia.

Authors: Cyrus Motamed; Karin Chedevergne; Frederic Deschamps; Lambros Tselikas; Christian Jayr
Journal: Anesth Pain Med Date: 2016-05-30

Mechanism of action of extradural analgesia.

1. The effect of age on the systemic absorption, disposition and pharmacodynamics of bupivacaine after epidural administration.

2. Somatosensory feedback from the limbs exerts inhibitory influences on central neural drive during whole body endurance exercise.

3. [The effect of central nervous modulation on the quality of epidural blockade.].

4. Desflurane anaesthesia in a patient with multiple sclerosis in total hip replacement.

5. President's address. Anaesthesia for biliary and pancreatic surgery.

6. Disposition and placental transfer of etidocaine in pregnancy.

Review 7. Clinical pharmacokinetics of epidural and spinal anaesthesia.

8. Analgesic dose-response relation in cervical epidural block.

Review 9. Horner's syndrome and trigeminal nerve palsy following epidural anaesthesia for obstetrics.

10. Contribution of Low-Dose Computerized Tomography With Digital Multiplanar Reconstructions in Thoracic Epidurography and Correlation With Sensory Block in Postoperative Analgesia.