Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Discovery of potent antagonists of the interaction between human double minute 2 and tumor suppressor p53.

× No keyword cloud information.

53 in total

1. Synthesis of cell-permeable stapled peptide dual inhibitors of the p53-Mdm2/Mdmx interactions via photoinduced cycloaddition.

Authors: Michael M Madden; Avinash Muppidi; Zhenyu Li; Xiaolong Li; Jiandong Chen; Qing Lin
Journal: Bioorg Med Chem Lett Date: 2011-01-07 Impact factor: 2.823

Review 2. Understanding protein non-folding.

Authors: Vladimir N Uversky; A Keith Dunker
Journal: Biochim Biophys Acta Date: 2010-02-01

3. Development of small molecules designed to modulate protein-protein interactions.

Authors: Ye Che; Bernard R Brooks; Garland R Marshall
Journal: J Comput Aided Mol Des Date: 2006-04-19 Impact factor: 3.686

Review 4. Targeting protein-protein interfaces using macrocyclic peptides.

Authors: Meng Gao; Kui Cheng; Hang Yin
Journal: Biopolymers Date: 2015-07 Impact factor: 2.505

5. Beta-peptides with improved affinity for hDM2 and hDMX.

Authors: Elizabeth A Harker; Douglas S Daniels; Danielle A Guarracino; Alanna Schepartz
Journal: Bioorg Med Chem Date: 2009-01-23 Impact factor: 3.641

6. Targeting tumor suppressor networks for cancer therapeutics.

Authors: Xuning Emily Guo; Bryan Ngo; Aram Sandaldjian Modrek; Wen-Hwa Lee
Journal: Curr Drug Targets Date: 2014-01 Impact factor: 3.465

7. Design and Synthesis of Functionalized Trisaccharides as p53-Peptide Mimics.

Authors: Kaori Sakurai; Daniel Kahne
Journal: Tetrahedron Lett Date: 2010-07-21 Impact factor: 2.415

Review 8. Dysregulation of apoptotic signaling in cancer: molecular mechanisms and therapeutic opportunities.

Authors: Jessica Plati; Octavian Bucur; Roya Khosravi-Far
Journal: J Cell Biochem Date: 2008-07-01 Impact factor: 4.429

9. Doxorubicin and 5-fluorouracil induced accumulation and transcriptional activity of p53 are independent of the phosphorylation at serine 15 in MCF-7 breast cancer cells.

Authors: Matthew T Balmer; Ryan D Katz; Si Liao; James S Goodwine; Susannah Gal
Journal: Cancer Biol Ther Date: 2014-05-06 Impact factor: 4.742

10. Peptide, Peptidomimetic, and Small-molecule Antagonists of the p53-HDM2 Protein-Protein Interaction.

Authors: Peter M Fischer
Journal: Int J Pept Res Ther Date: 2006-03-15 Impact factor: 1.931