Literature DB >> 10966708

Mediastinal lymphadenopathy: diagnostic yield of transbronchial mediastinal lymph node biopsy with CT fluoroscopic guidance-initial experience.

S N Goldberg1, V Raptopoulos, P M Boiselle, K J Edinburgh, A Ernst.   

Abstract

PURPOSE: To determine whether the use of computed tomographic (CT) fluoroscopy to guide transbronchial needle aspiration (TBNA) of mediastinal lymph nodes can improve the diagnostic yield.
MATERIALS AND METHODS: CT fluoroscopy was used to guide TBNA in 12 consecutive patients with mediastinal lymphadenopathy who had previously undergone nondiagnostic conventional TBNA. CT fluoroscopy was used to confirm the location of the biopsy needle by using a "quick-check" technique (ie, fluoroscopy was performed sparingly after needle insertion). The location of each needle, the total procedural and fluoroscopic times, and any complications were recorded.
RESULTS: All CT fluoroscopic procedures were performed in less than 1 hour, and a tissue diagnosis was established in all patients. Eighteen lymph nodes with a diameter of 0.8-2.4 cm were sampled with 116 needle passes. CT fluoroscopy documented inadequate positioning in 48 of the 116 (41.3%) needle passes. Eighteen (15.5%) needles did not fully penetrate the tracheobronchial tree. Six needles (5.2%) were placed into the great vessels. Malignant disease was diagnosed in nine patients, and benign disease was diagnosed in three. The mean fluoroscopic exposure time was 20.5 seconds +/- 12.7. No pneumothoraces or substantial hemorrhage were observed.
CONCLUSION: CT fluoroscopic guidance for TBNA procedures is a safe and efficient means of providing diagnostic material and should be considered for patients who have previously undergone nondiagnostic blinded TBNA.

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Year:  2000        PMID: 10966708     DOI: 10.1148/radiology.216.3.r00se32764

Source DB:  PubMed          Journal:  Radiology        ISSN: 0033-8419            Impact factor:   11.105


  3 in total

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Authors:  Thomas R Gildea; Peter J Mazzone; Demet Karnak; Moulay Meziane; Atul C Mehta
Journal:  Am J Respir Crit Care Med       Date:  2006-07-27       Impact factor: 21.405

2.  Apparent Diffusion Coefficient Measurement in Mediastinal Lymphadenopathies: Differentiation between Benign and Malignant Lesions.

Authors:  Fethi Emre Ustabasioglu; Cesur Samanci; Deniz Alis; Nilay Sengul Samanci; Osman Kula; Deniz Cebi Olgun
Journal:  J Clin Imaging Sci       Date:  2017-03-06

3.  Diffusion-weighted magnetic resonance imaging for differentiating between benign and malignant thoracic lymph nodes: a meta-analysis.

Authors:  Francisco de Souza Santos; Nupur Verma; Guilherme Watte; Edson Marchiori; Tan-Lucien H Mohammed; Tássia Machado Medeiros; Bruno Hochhegger
Journal:  Radiol Bras       Date:  2021 Jul-Aug
  3 in total

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