Literature DB >> 10966454

Spindle assembly in animal cells.

D A Compton1.   

Abstract

Chromosome segregation during mitosis and meiosis is driven by a complex superstructure called the spindle. Microtubules are the primary structural component of spindles, and spindle assembly and function are intimately linked to the intrinsic dynamics of microtubules. This review summarizes spindle structure and highlights recent findings regarding the mechanisms and molecules involved in organizing microtubules into spindles. In addition, mechanisms for chromosome movement and segregation are discussed.

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Year:  2000        PMID： 10966454     DOI： 10.1146/annurev.biochem.69.1.95

Source DB:  PubMed          Journal:  Annu Rev Biochem        ISSN： 0066-4154            Impact factor:   23.643


  107 in total

1.  Self-organization of a radial microtubule array by dynein-dependent nucleation of microtubules.

Authors:  I Vorobjev; V Malikov; V Rodionov
Journal:  Proc Natl Acad Sci U S A       Date:  2001-08-14       Impact factor: 11.205

2.  A kinesin mutant with an atypical bipolar spindle undergoes normal mitosis.

Authors:  A I Marcus; W Li; H Ma; R J Cyr
Journal:  Mol Biol Cell       Date:  2003-04       Impact factor: 4.138

3.  Ran GTPase cycle and importins alpha and beta are essential for spindle formation and nuclear envelope assembly in living Caenorhabditis elegans embryos.

Authors:  Peter Askjaer; Vincent Galy; Eva Hannak; Iain W Mattaj
Journal:  Mol Biol Cell       Date:  2002-12       Impact factor: 4.138

4.  Intrinsic disorder in dynein intermediate chain modulates its interactions with NudE and dynactin.

Authors:  Afua Nyarko; Yujuan Song; Elisar Barbar
Journal:  J Biol Chem       Date:  2012-06-05       Impact factor: 5.157

5.  The chromokinesin, KLP3A, dives mitotic spindle pole separation during prometaphase and anaphase and facilitates chromatid motility.

Authors:  Mijung Kwon; Sandra Morales-Mulia; Ingrid Brust-Mascher; Gregory C Rogers; David J Sharp; Jonathan M Scholey
Journal:  Mol Biol Cell       Date:  2003-10-03       Impact factor: 4.138

6.  Importin alpha-regulated nucleation of microtubules by TPX2.

Authors:  Christoph A Schatz; Rachel Santarella; Andreas Hoenger; Eric Karsenti; Iain W Mattaj; Oliver J Gruss; Rafael E Carazo-Salas
Journal:  EMBO J       Date:  2003-05-01       Impact factor: 11.598

7.  Importin alpha/beta and Ran-GTP regulate XCTK2 microtubule binding through a bipartite nuclear localization signal.

Authors:  Stephanie C Ems-McClung; Yixian Zheng; Claire E Walczak
Journal:  Mol Biol Cell       Date:  2003-09-17       Impact factor: 4.138

8.  A pathway containing the Ipl1/aurora protein kinase and the spindle midzone protein Ase1 regulates yeast spindle assembly.

Authors:  Chitra V Kotwaliwale; Stéphanie Buvelot Frei; Bodo M Stern; Sue Biggins
Journal:  Dev Cell       Date:  2007-09       Impact factor: 12.270

9.  The zebra fish cassiopeia mutant reveals that SIL is required for mitotic spindle organization.

Authors:  Kathleen L Pfaff; Christian T Straub; Ken Chiang; Daniel M Bear; Yi Zhou; Leonard I Zon
Journal:  Mol Cell Biol       Date:  2007-06-18       Impact factor: 4.272

10.  A functional relationship between NuMA and kid is involved in both spindle organization and chromosome alignment in vertebrate cells.

Authors:  Aime A Levesque; Louisa Howard; Michael B Gordon; Duane A Compton
Journal:  Mol Biol Cell       Date:  2003-06-13       Impact factor: 4.138
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