Literature DB >> 10966076

Argifin, a new chitinase inhibitor, produced by Gliocladium sp. FTD-0668. I. Taxonomy, fermentation, and biological activities.

S Omura1, N Arai, Y Yamaguchi, R Masuma, Y Iwai, M Namikoshi, A Turberg, H Kölbl, K Shiomi.   

Abstract

A new chitinase inhibitor, named argifin, was isolated from the cultured broth of a fungal strain FTD-0668. The strain was identified as Gliocladium sp. from morphological characteristics. The IC50 value of argifin against Lucilia cuprina chitinase was 3.7 microM. Argifin arrested the moult of cockroach larvae upon injection into the ventral abdominal part.

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Year:  2000        PMID： 10966076     DOI： 10.7164/antibiotics.53.603

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  12 in total

1.  Fully deacetylated chitooligosaccharides act as efficient glycoside hydrolase family 18 chitinase inhibitors.

Authors:  Lei Chen; Yong Zhou; Mingbo Qu; Yong Zhao; Qing Yang
Journal:  J Biol Chem       Date:  2014-05-14       Impact factor: 5.157

2.  Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms.

Authors:  Supansa Pantoom; Ingrid R Vetter; Heino Prinz; Wipa Suginta
Journal:  J Biol Chem       Date:  2011-04-29       Impact factor: 5.157

3.  Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor.

Authors:  Tomoyasu Hirose; Nobuo Maita; Hiroaki Gouda; Jun Koseki; Tsuyoshi Yamamoto; Akihiro Sugawara; Hirofumi Nakano; Shuichi Hirono; Kazuro Shiomi; Takeshi Watanabe; Hisaaki Taniguchi; K Barry Sharpless; Satoshi Omura; Toshiaki Sunazuka
Journal:  Proc Natl Acad Sci U S A       Date:  2013-09-16       Impact factor: 11.205

Review 4.  Novel methylxanthine derivative-mediated anti-inflammatory effects in inflammatory bowel disease.

Authors:  In-Ah Lee; Alan Kamba; Daren Low; Emiko Mizoguchi
Journal:  World J Gastroenterol       Date:  2014-02-07       Impact factor: 5.742

5.  Natural product-guided discovery of a fungal chitinase inhibitor.

Authors:  Christina L Rush; Alexander W Schüttelkopf; Ramon Hurtado-Guerrero; David E Blair; Adel F M Ibrahim; Stéphanie Desvergnes; Ian M Eggleston; Daan M F van Aalten
Journal:  Chem Biol       Date:  2010-12-22

Review 6.  Recent development of two chitinase inhibitors, Argifin and Argadin, produced by soil microorganisms.

Authors:  Tomoyasu Hirose; Toshiaki Sunazuka; Satoshi Omura
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2010       Impact factor: 3.493

Review 7.  Fungal chitinases: diversity, mechanistic properties and biotechnological potential.

Authors:  Lukas Hartl; Simone Zach; Verena Seidl-Seiboth
Journal:  Appl Microbiol Biotechnol       Date:  2011-12-02       Impact factor: 4.813

8.  Total synthesis of the putative structure of the proposed Banyasin A.

Authors:  Xuguang Gao; Qi Ren; Sun Choi; Zhengshuang Xu; Tao Ye
Journal:  Front Chem       Date:  2015-03-17       Impact factor: 5.221

9.  Interactions among filamentous fungi Aspergillus niger, Fusarium verticillioides and Clonostachys rosea: fungal biomass, diversity of secreted metabolites and fumonisin production.

Authors:  Subhankar Chatterjee; Yi Kuang; Richard Splivallo; Paramita Chatterjee; Petr Karlovsky
Journal:  BMC Microbiol       Date:  2016-05-10       Impact factor: 3.605

10.  Structure-based dissection of the natural product cyclopentapeptide chitinase inhibitor argifin.

Authors:  Ole A Andersen; Amit Nathubhai; Mark J Dixon; Ian M Eggleston; Daan M F van Aalten
Journal:  Chem Biol       Date:  2008-03
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