Literature DB >> 10964444

An NMR spectroscopic identity test for the control of the capsular polysaccharide from Haemophilus influenzae type b.

X Lemercinier1, C Jones.   

Abstract

We describe the use of Nuclear Magnetic Resonance (NMR) spectroscopy to control the identity of purified bulk capsular polysaccharide [called poly(ribosylribitolphosphate) or PRP] from Haemophilus influenzae type b (Hib), and derivatised forms, used in the production of Hib polysaccharide-protein conjugate vaccines. We describe the approaches we have developed to validate this test. Copyright 2000 The International Association for Biologicals.

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Year:  2000        PMID： 10964444     DOI： 10.1006/biol.2000.0255

Source DB:  PubMed          Journal:  Biologicals        ISSN： 1045-1056            Impact factor:   1.856


  5 in total

1.  A study of physico-chemical interactions between Haemophilus influenzae type b and meningococcus group C conjugate vaccines.

Authors:  Robert B D Otto; Dennis T Crane; Barbara Bolgiano
Journal:  Afr Health Sci       Date:  2007-12       Impact factor: 0.927

2.  Cross-reactivity of Haemophilus influenzae type a and b polysaccharides: molecular modeling and conjugate immunogenicity studies.

Authors:  Nicole I Richardson; Michelle M Kuttel; Frank St Michael; Chantelle Cairns; Andrew D Cox; Neil Ravenscroft
Journal:  Glycoconj J       Date:  2021-09-07       Impact factor: 2.916

3.  Nuclear Magnetic Resonance (NMR) Study for the Detection and Quantitation of Cholesterol in HSV529 Therapeutic Vaccine Candidate.

Authors:  Rahima Khatun; Howard Hunter; Webster Magcalas; Yi Sheng; Bruce Carpick; Marina Kirkitadze
Journal:  Comput Struct Biotechnol J       Date:  2016-11-01       Impact factor: 7.271

4.  Chemical structure, conjugation, and cross-reactivity of Bacillus pumilus Sh18 cell wall polysaccharide.

Authors:  Joanna Kubler-Kielb; Bruce Coxon; Rachel Schneerson
Journal:  J Bacteriol       Date:  2004-10       Impact factor: 3.490

5.  Two variants among Haemophilus influenzae serotype b strains with distinct bcs4, hcsA and hcsB genes display differences in expression of the polysaccharide capsule.

Authors:  Leo Schouls; Han van der Heide; Sandra Witteveen; Bert Zomer; Arie van der Ende; Marina Burger; Corrie Schot
Journal:  BMC Microbiol       Date:  2008-02-25       Impact factor: 3.605
  5 in total

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