| Literature DB >> 10962252 |
A Plenevaux1, C Lemaire, J Aerts, G Lacan, D Rubins, W P Melega, C Brihaye, C Degueldre, S Fuchs, E Salmon, P Maquet, S Laureys, P Damhaut, D Weissmann, D Le Bars, J F Pujol, A Luxen.
Abstract
This paper summarizes the present status of the researches conducted with [(18)F]4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p-fluorobenzamido ]ethyl]-piperazine known as [(18)F]p-MPPF, a new 5-HT(1A) antagonist for the study of the serotonergic neurotransmission with positron emission tomography (PET). This includes chemistry, radiochemistry, animal data (rats, cats, and monkeys) with autoradiography and PET, human data with PET, toxicity, and metabolism.Entities:
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Year: 2000 PMID： 10962252 DOI： 10.1016/s0969-8051(00)00113-x
Source DB: PubMed Journal: Nucl Med Biol ISSN： 0969-8051 Impact factor: 2.408