Literature DB >> 10960902

Protective effect of leaf extract of Ficus hispida Linn. against paracetamol-induced hepatotoxicity in rats.

S C Mandal1, B Saraswathi, C K Kumar, S Mohana Lakshmi, B C Maiti.   

Abstract

The methanol extract of the leaves of Ficus hispida Linn. (Moraceae) was evaluated for hepatoprotective activity in rats by inducing acute liver damage by paracetamol (750 mg/kg, p.o.). The extract at an oral dose of 400 mg/kg exhibited a significant protective effect by lowering the serum levels of transaminase (SGOT and SGPT), bilirubin and alkaline phosphatase (ALP). These biochemical observations were supplemented by histopathological examination of liver sections. The activity of extract was also comparable to that of Liv-52 a known hepatoprotective formulation. Copyright 2000 John Wiley & Sons, Ltd.

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Year:  2000        PMID: 10960902     DOI: 10.1002/1099-1573(200009)14:6<457::aid-ptr610>3.0.co;2-8

Source DB:  PubMed          Journal:  Phytother Res        ISSN: 0951-418X            Impact factor:   5.878


  8 in total

1.  Liv.52 protects HepG2 cells from oxidative damage induced by tert-butyl hydroperoxide.

Authors:  S Vidyashankar; S K Mitra; Krishna S Nandakumar
Journal:  Mol Cell Biochem       Date:  2009-07-22       Impact factor: 3.396

2.  Liv.52 regulates ethanol induced PPARgamma and TNF alpha expression in HepG2 cells.

Authors:  Shankar K Mitra; Sandeep Ravi Varma; Ashok Godavarthi; Krishna S Nandakumar
Journal:  Mol Cell Biochem       Date:  2008-05-01       Impact factor: 3.396

3.  Antihyperglycemic activities of leaves of three edible fruit plants (Averrhoa carambola, Ficus hispida and Syzygium samarangense) of Bangladesh.

Authors:  Shejuty Shahreen; Joyanta Banik; Abdul Hafiz; Shahnaz Rahman; Anahita Tanzia Zaman; Md Abu Shoyeb; Majeedul H Chowdhury; Mohammed Rahmatullah
Journal:  Afr J Tradit Complement Altern Med       Date:  2011-12-29

4.  Ficus hispida Linn.: A review of its pharmacognostic and ethnomedicinal properties.

Authors:  Mohammad Ali; Nisha Chaudhary
Journal:  Pharmacogn Rev       Date:  2011-01

5.  Cytotoxic Effects of Different Extracts and Latex of Ficus carica L. on HeLa cell Line.

Authors:  Ghadam Ali Khodarahmi; Nasrollah Ghasemi; Farshid Hassanzadeh; Marzieh Safaie
Journal:  Iran J Pharm Res       Date:  2011       Impact factor: 1.696

6.  Ficus hispida Bark Extract Prevents Nociception, Inflammation, and CNS Stimulation in Experimental Animal Model.

Authors:  Md Sariful Islam Howlader; Md Afjalus Siraj; Shubhra Kanti Dey; Arpona Hira; Arif Ahmed; Md Hemayet Hossain
Journal:  Evid Based Complement Alternat Med       Date:  2017-04-12       Impact factor: 2.629

7.  In vitro Cytotoxicity and Apoptotic Assay in HT-29 Cell Line Using Ficus hispida Linn: Leaves Extract.

Authors:  Jayalalitha Sathiyamoorthy; Natarajan Sudhakar
Journal:  Pharmacogn Mag       Date:  2018-01-31       Impact factor: 1.085

8.  Hepatoprotective Effect of Ficus carica Leaf Extract on Mice Intoxicated with Carbon Tetrachloride.

Authors:  Nasrin Aghel; Heibatollah Kalantari; Shohreh Rezazadeh
Journal:  Iran J Pharm Res       Date:  2011       Impact factor: 1.696

  8 in total

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