Literature DB >> 10960795

Developmental expression of the Xenopus Nkx2-1 and Nkx2-4 genes.

E M Small1, S A Vokes, R J Garriock, D Li, P A Krieg.   

Abstract

The homeodomain transcription factor Nkx2-1 (TTF-1) plays an essential role in the development of the thyroid, lung and ventral forebrain. We report the cloning and developmental expression patterns of two Xenopus NK-2 genes, Nkx2-1 and Nkx2-4, that are closely related to Nkx2-1. These genes show readily distinguishable expression patterns during development. Similar to its orthologues in chicken and mouse, the Xenopus Nkx2-1 gene is expressed in the developing thyroid, lung, and ventral forebrain. In contrast, expression of Nkx2-4 is specifically localized to the ventral diencephalon.

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Year:  2000        PMID： 10960795     DOI： 10.1016/s0925-4773(00)00400-7

Source DB:  PubMed          Journal:  Mech Dev        ISSN： 0925-4773            Impact factor:   1.882


  18 in total

1.  A Molecular atlas of Xenopus respiratory system development.

Authors:  Scott A Rankin; Hong Thi Tran; Marcin Wlizla; Pamela Mancini; Emily T Shifley; Sean D Bloor; Lu Han; Kris Vleminckx; Susan E Wert; Aaron M Zorn
Journal:  Dev Dyn       Date:  2014-09-11       Impact factor: 3.780

2.  Lung epithelial branching program antagonizes alveolar differentiation.

Authors:  Daniel R Chang; Denise Martinez Alanis; Rachel K Miller; Hong Ji; Haruhiko Akiyama; Pierre D McCrea; Jichao Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2013-09-20       Impact factor: 11.205

3.  A transgene targeted to the zebrafish nkx2.4b locus drives specific green fluorescent protein expression and disrupts thyroid development.

Authors:  David A Hutcheson; Yuanyuan Xie; Priscilla Figueroa; Richard I Dorsky
Journal:  Dev Dyn       Date:  2020-08-05       Impact factor: 3.780

4.  Specification of select hypothalamic circuits and innate behaviors by the embryonic patterning gene dbx1.

Authors:  Katie Sokolowski; Shigeyuki Esumi; Tsutomu Hirata; Yasman Kamal; Tuyen Tran; Andrew Lam; Livio Oboti; Sherri-Chanelle Brighthaupt; Manar Zaghlula; Jennifer Martinez; Svetlana Ghimbovschi; Susan Knoblach; Alessandra Pierani; Nobuaki Tamamaki; Nirao M Shah; Kevin S Jones; Joshua G Corbin
Journal:  Neuron       Date:  2015-04-09       Impact factor: 17.173

5.  Choice of either beta-catenin or Groucho/TLE as a co-factor for Xtcf-3 determines dorsal-ventral cell fate of diencephalon during Xenopus development.

Authors:  Saori Tsuji; Chikara Hashimoto
Journal:  Dev Genes Evol       Date:  2005-03-04       Impact factor: 0.900

6.  C/EBPalpha initiates primitive myelopoiesis in pluripotent embryonic cells.

Authors:  Yaoyao Chen; Ricardo M B Costa; Nick R Love; Ximena Soto; Martin Roth; Roberto Paredes; Enrique Amaya
Journal:  Blood       Date:  2009-05-06       Impact factor: 22.113

7.  Suppression of Bmp4 signaling by the zinc-finger repressors Osr1 and Osr2 is required for Wnt/β-catenin-mediated lung specification in Xenopus.

Authors:  Scott A Rankin; Alyssa L Gallas; Ana Neto; José Luis Gómez-Skarmeta; Aaron M Zorn
Journal:  Development       Date:  2012-07-12       Impact factor: 6.868

8.  Retinoic acid-activated Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification.

Authors:  Tiejun Zhang; Xiaogang Guo; Yonglong Chen
Journal:  PLoS One       Date:  2013-05-31       Impact factor: 3.240

Review 9.  Xenopus leads the way: Frogs as a pioneering model to understand the human brain.

Authors:  Cameron R T Exner; Helen Rankin Willsey
Journal:  Genesis       Date:  2020-12-27       Impact factor: 2.487

10.  Prolonged FGF signaling is necessary for lung and liver induction in Xenopus.

Authors:  Emily T Shifley; Alan P Kenny; Scott A Rankin; Aaron M Zorn
Journal:  BMC Dev Biol       Date:  2012-09-18       Impact factor: 1.978
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