Literature DB >> 10959046

Adhesion-linked kinases in cancer; emphasis on src, focal adhesion kinase and PI 3-kinase.

R J Jones1, V G Brunton, M C Frame.   

Abstract

Our understanding of the complex signal transduction pathways involved in signalling within cancer cells, between cancer cells and between cancer cells and their environment has increased dramatically in recent years. Here we concentrate on three non-receptor kinases: Src, focal adhesion kinase (FAK) and phosphatidylinositol 3-kinase (PI 3-kinase). These form part of a complex network of intracellular signals which is thought to be important in regulating cancer cells.

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Year:  2000        PMID： 10959046     DOI： 10.1016/s0959-8049(00)00153-2

Source DB:  PubMed          Journal:  Eur J Cancer        ISSN： 0959-8049            Impact factor:   9.162


  31 in total

1.  Trask phosphorylation defines the reverse mode of a phosphotyrosine signaling switch that underlies cell anchorage state.

Authors:  Danislav S Spassov; Ching H Wong; Mark M Moasser
Journal:  Cell Cycle       Date:  2011-04-15       Impact factor: 4.534

Review 2.  FIP200, a key signaling node to coordinately regulate various cellular processes.

Authors:  Boyi Gan; Jun-Lin Guan
Journal:  Cell Signal       Date:  2007-11-01       Impact factor: 4.315

3.  Expression, purification, and bioactivity of GST-fused v-Src from a bacterial expression system.

Authors:  Xing-Guo Gong; Jing Ji; Jie Xie; Yuan Zhou; Jun-Yan Zhang; Wen-Tao Zhong
Journal:  J Zhejiang Univ Sci B       Date:  2006-01       Impact factor: 3.066

Review 4.  SH3 domains: modules of protein-protein interactions.

Authors:  Natalya Kurochkina; Udayan Guha
Journal:  Biophys Rev       Date:  2012-06-20

5.  Malignant transformation but not normal cell growth depends on signal transducer and activator of transcription 3.

Authors:  Karni Schlessinger; David E Levy
Journal:  Cancer Res       Date:  2005-07-01       Impact factor: 12.701

6.  Sublethal concentrations of the platinum(II) complex [Pt(O,O'-acac)(gamma-acac)(DMS)] alter the motility and induce anoikis in MCF-7 cells.

Authors:  Antonella Muscella; Nadia Calabriso; Carla Vetrugno; Loredana Urso; Francesco Paolo Fanizzi; Sandra Angelica De Pascali; Santo Marsigliante
Journal:  Br J Pharmacol       Date:  2010-07       Impact factor: 8.739

Review 7.  Dynamic interplay between adhesion surfaces in carcinomas: Cell-cell and cell-matrix crosstalk.

Authors:  Yvonne E Smith; Sri HariKrishna Vellanki; Ann M Hopkins
Journal:  World J Biol Chem       Date:  2016-02-26

8.  Gene array and fluorescence in situ hybridization biomarkers of activity of saracatinib (AZD0530), a Src inhibitor, in a preclinical model of colorectal cancer.

Authors:  John J Arcaroli; Basel M Touban; Aik Choon Tan; Marileila Varella-Garcia; Rebecca W Powell; S Gail Eckhardt; Paul Elvin; Dexiang Gao; Wells A Messersmith
Journal:  Clin Cancer Res       Date:  2010-08-03       Impact factor: 12.531

9.  Negative regulation of FAK signaling by SOCS proteins.

Authors:  Enbo Liu; Jean-François Côté; Kristiina Vuori
Journal:  EMBO J       Date:  2003-10-01       Impact factor: 11.598

10.  Proteome-wide analysis of protein abundance and turnover remodelling during oncogenic transformation of human breast epithelial cells.

Authors:  Tony Ly; Aki Endo; Alejandro Brenes; Marek Gierlinski; Vackar Afzal; Andrea Pawellek; Angus I Lamond
Journal:  Wellcome Open Res       Date:  2018-05-02
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