Literature DB >> 10958950

A case of near-triploidy in chronic myelogenous leukemia.

B Roland1, W B Blahey.   

Abstract

A 61-year-old woman with chronic myelogenous leukemia (CML) in accelerated phase had a near-triploid bone-marrow karyotype. This karyotype is an unusual finding in CML, as we review 12 previously published similar cases. These patients do not differ clinically from other patients with CML in blast crisis. The cytogenetic features of near-diploid and near-triploid CML are similar, except that relative loss of chromosomes is more common and that isochromosome 17q has not been reported in near-triploid CML.

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Year:  2000        PMID: 10958950     DOI: 10.1016/s0165-4608(00)00227-2

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN: 0165-4608


  4 in total

1.  Philadelphia-positive case negative for JAK2 V617F mutation with hyperdiploidic karyotype: A case report.

Authors:  Dragomira Nikolova; Vera Damyanova; Vasil Hrischev; Maria Markova; Lubomir Mitev; Aselina Asenova; Atanas Radinov; Draga Toncheva
Journal:  Mol Clin Oncol       Date:  2019-10-04

2.  A case of near-triploidy in myelodysplastic syndrome with del(5q) combined with del(1p) and del(13q).

Authors:  Bo-Ram Kim; Ji-Eun Kim; Kwang-Sook Woo; Kyeong-Hee Kim; Jeong-Man Kim; Suee Lee; Lisa G Shaffer; Jin-Yeong Han
Journal:  Ann Lab Med       Date:  2012-06-20       Impact factor: 3.464

3.  Hyperdiploidy associated with T315I mutation in BCR-ABL kinase domain in an accelerated phase-chronic myeloid leukemia case.

Authors:  Walid Al-Achkar; Faten Moassass; Adnan Ikhtiar; Thomas Liehr; Moneeb Abdullah Kassem Othman; Abdulsamad Wafa
Journal:  Mol Cytogenet       Date:  2014-11-29       Impact factor: 2.009

4.  Masked inv dup(22)(q11.23), tetrasomy 8 and trisomy 19 in a blast crisis-chronic myeloid leukemia after interrupted Imatinib-treatment.

Authors:  Abdulsamad Wafa; Suher Almedani; Thomas Liehr; Walid Al-Achkar
Journal:  Mol Cytogenet       Date:  2015-12-23       Impact factor: 2.009

  4 in total

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