Literature DB >> 10957968

O6-alkylguanine-DNA alkyltransferase assay.

A J Watson1, G P Margison.   

Abstract

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Year:  2000        PMID： 10957968     DOI： 10.1385/1-59259-068-3:49

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


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  17 in total

1.  Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoietic stem cells.

Authors:  Michael D Milsom; Moran Jerabek-Willemsen; Chad E Harris; Axel Schambach; Emily Broun; Jeff Bailey; Michael Jansen; David Schleimer; Kalpana Nattamai; Jamie Wilhelm; Amanda Watson; Hartmut Geiger; Geoffrey P Margison; Thomas Moritz; Christopher Baum; Jürgen Thomale; David A Williams
Journal:  Cancer Res       Date:  2008-08-01       Impact factor: 12.701

2.  Atl1 regulates choice between global genome and transcription-coupled repair of O(6)-alkylguanines.

Authors:  Vitaly F Latypov; Julie L Tubbs; Amanda J Watson; Andrew S Marriott; Gail McGown; Mary Thorncroft; Oliver J Wilkinson; Pattama Senthong; Amna Butt; Andrew S Arvai; Christopher L Millington; Andrew C Povey; David M Williams; Mauro F Santibanez-Koref; John A Tainer; Geoffrey P Margison
Journal:  Mol Cell       Date:  2012-05-31       Impact factor: 17.970

3.  Folate deficiency alters hepatic and colon MGMT and OGG-1 DNA repair protein expression in rats but has no effect on genome-wide DNA methylation.

Authors:  Susan J Duthie; George Grant; Lynn P Pirie; Amanda J Watson; Geoffrey P Margison
Journal:  Cancer Prev Res (Phila)       Date:  2010-01

4.  Expression of O-Alkylguanine-DNA Alkyltransferase in Normal and Malignant Bladder Tissue of Egyptian Patients.

Authors:  Abir A Saad; Heba Sh Kassem; Andrew C Povey; Geoffrey P Margison
Journal:  J Nucleic Acids       Date:  2010-10-17

5.  Development of an O(6)-alkylguanine-DNA alkyltransferase assay based on covalent transfer of the benzyl moiety from [benzene-3H]O(6)-benzylguanine to the protein.

Authors:  Kimiko Ishiguro; Krishnamurthy Shyam; Philip G Penketh; Alan C Sartorelli
Journal:  Anal Biochem       Date:  2008-08-20       Impact factor: 3.365

6.  Tumor O(6)-methylguanine-DNA methyltransferase inactivation by oral lomeguatrib.

Authors:  Amanda J Watson; Ami Sabharwal; Mary Thorncroft; Gail McGown; Richard Kerr; Stana Bojanic; Zahir Soonawalla; Alexandra King; Andrea Miller; Sue Waller; Hing Leung; Geoffrey P Margison; Mark R Middleton
Journal:  Clin Cancer Res       Date:  2010-01-12       Impact factor: 12.531

7.  Novel synthesis of O6-alkylguanine containing oligodeoxyribonucleotides as substrates for the human DNA repair protein, O6-methylguanine DNA methyltransferase (MGMT).

Authors:  Takayuki Shibata; Nicola Glynn; T Brian H McMurry; R Stanley McElhinney; Geoffrey P Margison; David M Williams
Journal:  Nucleic Acids Res       Date:  2006-04-11       Impact factor: 16.971

8.  Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI.

Authors:  Dhanalakshmi Chinnasamy; Michael D Milsom; James Shaffer; James Neuenfeldt; Aimen F Shaaban; Geoffrey P Margison; Leslie J Fairbairn; Nachimuthu Chinnasamy
Journal:  Virol J       Date:  2006-03-15       Impact factor: 4.099

9.  O(6)-methylguanine-DNA methyltransferase depletion and DNA damage in patients with melanoma treated with temozolomide alone or with lomeguatrib.

Authors:  A J Watson; M R Middleton; G McGown; M Thorncroft; M Ranson; P Hersey; G McArthur; I D Davis; D Thomson; J Beith; A Haydon; R Kefford; P Lorigan; P Mortimer; A Sabharwal; O Hayward; G P Margison
Journal:  Br J Cancer       Date:  2009-04-21       Impact factor: 7.640

10.  A phase I study of extended dosing with lomeguatrib with temozolomide in patients with advanced melanoma.

Authors:  R F Kefford; N P B Thomas; P G Corrie; C Palmer; E Abdi; D Kotasek; J Beith; M Ranson; P Mortimer; A J Watson; G P Margison; M R Middleton
Journal:  Br J Cancer       Date:  2009-03-31       Impact factor: 7.640
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