Literature DB >> 10956543

Synthesis of ecteinascidin ET-743 and phthalascidin Pt-650 from cyanosafracin B.

C Cuevas1, M Pérez, M J Martín, J L Chicharro, C Fernández-Rivas, M Flores, A Francesch, P Gallego, M Zarzuelo, F de La Calle, J García, C Polanco, I Rodríguez, I Manzanares.   

Abstract

An efficient new process is described for the synthesis of ecteinascidin ET-743 (1) and phthalascidin (2), starting from readily available cyanosafracin B (3).

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Year:  2000        PMID： 10956543     DOI： 10.1021/ol0062502

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  38 in total

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Review 4.  Lessons from the past and charting the future of marine natural products drug discovery and chemical biology.

Authors:  William H Gerwick; Bradley S Moore
Journal:  Chem Biol       Date:  2012-01-27

Review 5.  Drug development from marine natural products.

Authors:  Tadeusz F Molinski; Doralyn S Dalisay; Sarah L Lievens; Jonel P Saludes
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6.  INTEGRATED APPROACHES TO THE CONFIGURATIONAL ASSIGNMENT OF MARINE NATURAL PRODUCTS.

Authors:  Tadeusz F Molinski; Brandon I Morinaka
Journal:  Tetrahedron       Date:  2012-11-18       Impact factor: 2.457

Review 7.  Microbial natural products: molecular blueprints for antitumor drugs.

Authors:  Lesley-Ann Giddings; David J Newman
Journal:  J Ind Microbiol Biotechnol       Date:  2013-09-03       Impact factor: 3.346

8.  Accelerating the semisynthesis of alkaloid-based drugs through metabolic engineering.

Authors:  Amy M Ehrenworth; Pamela Peralta-Yahya
Journal:  Nat Chem Biol       Date:  2017-02-15       Impact factor: 15.040

9.  Concise total syntheses of (-)-jorunnamycin A and (-)-jorumycin enabled by asymmetric catalysis.

Authors:  Eric R Welin; Aurapat Ngamnithiporn; Max Klatte; Guillaume Lapointe; Gerit M Pototschnig; Martina S J McDermott; Dylan Conklin; Christopher D Gilmore; Pamela M Tadross; Christopher K Haley; Kenji Negoro; Emil Glibstrup; Christian U Grünanger; Kevin M Allan; Scott C Virgil; Dennis J Slamon; Brian M Stoltz
Journal:  Science       Date:  2018-12-20       Impact factor: 47.728

10.  Characterization of the saframycin A gene cluster from Streptomyces lavendulae NRRL 11002 revealing a nonribosomal peptide synthetase system for assembling the unusual tetrapeptidyl skeleton in an iterative manner.

Authors:  Lei Li; Wei Deng; Jie Song; Wei Ding; Qun-Fei Zhao; Chao Peng; Wei-Wen Song; Gong-Li Tang; Wen Liu
Journal:  J Bacteriol       Date:  2007-11-02       Impact factor: 3.490
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