Literature DB >> 10956459

Fluorination of thiocarbonyl compounds with Bis(2-methoxyethyl)aminosulfur trifluoride (Deoxo-fluor reagent): A facile synthesis of gem-difluorides

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Abstract

A variety of thiocarbonyl derivatives (thioketone, thioester, thioamide, dithioester, and dithiocarbamate) were converted to the corresponding gem-difluorides in excellent yields on reaction with the fluorinating agent, bis(2-methoxyethyl)aminosulfur trifluoride, in the presence of SbCl(3).

Entities:  

Year:  2000        PMID： 10956459     DOI： 10.1021/jo000020j

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  5 in total

1.  n→π* Interactions Modulate the Disulfide Reduction Potential of Epidithiodiketopiperazines.

Authors:  Henry R Kilgore; Chase R Olsson; Kyan A D'Angelo; Mohammad Movassaghi; Ronald T Raines
Journal:  J Am Chem Soc       Date:  2020-08-21       Impact factor: 15.419

2.  Aminodifluorosulfinium salts: selective fluorination reagents with enhanced thermal stability and ease of handling.

Authors:  Alexandre L'heureux; Francis Beaulieu; Christopher Bennett; David R Bill; Simon Clayton; François Laflamme; Mahmoud Mirmehrabi; Sam Tadayon; David Tovell; Michel Couturier
Journal:  J Org Chem       Date:  2010-05-21       Impact factor: 4.354

3.  The vicinal difluoro motif: The synthesis and conformation of erythro- and threo- diastereoisomers of 1,2-difluorodiphenylethanes, 2,3-difluorosuccinic acids and their derivatives.

Authors:  David O'Hagan; Henry S Rzepa; Martin Schüler; Alexandra M Z Slawin
Journal:  Beilstein J Org Chem       Date:  2006-10-02       Impact factor: 2.883

4.  Synthesis of aryl 2-bromo-2-chloro-1,1-difluoroethyl ethers through the base-mediated reaction between phenols and halothane.

Authors:  Yukiko Karuo; Ayaka Kametani; Atsushi Tarui; Kazuyuki Sato; Kentaro Kawai; Masaaki Omote
Journal:  Beilstein J Org Chem       Date:  2021-01-11       Impact factor: 2.883

5.  Synthesis and structure-activity relationship studies of derivatives of the dual aromatase-sulfatase inhibitor 4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl sulfamate.

Authors:  L W Lawrence Woo; Paul M Wood; Christian Bubert; Mark P Thomas; Atul Purohit; Barry V L Potter
Journal:  ChemMedChem       Date:  2013-03-11       Impact factor: 3.466
  5 in total

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