Literature DB >> 10956458

Iodocyclization of O-(3-Cyclohexenyl)thiocarbamidates. An unexpected approach to vicinal cis-aminocyclohexenols

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Abstract

An unprecedented and unexpected iodocyclization of O-(3-cyclohexenyl)thiocarbamidates 2a-c to diiodides 7a-c, followed by alkaline hydrolysis and iodide elimination, has uncovered an alternative approach to vicinal cis-aminocyclohexenols 10a-c and 11a-c. This represents a new approach to these interesting building blocks.

Entities:  

Year:  2000        PMID: 10956458     DOI: 10.1021/jo991980c

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

1.  Intramolecular nitrogen delivery for the synthesis of C-glycosphingolipids. Application to the C-glycoside of the immunostimulant KRN7000.

Authors:  Ahmad S Altiti; David R Mootoo
Journal:  Org Lett       Date:  2014-02-21       Impact factor: 6.005

  1 in total

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