Literature DB >> 10956184

3,5-Disubstituted-4-hydroxyphenyls linked to 3-hydroxy-2-methyl-4(1H)-pyridinone: potent inhibitors of lipid peroxidation and cell toxicity.

D Bebbington1, N J Monck, S Gaur, A M Palmer, K Benwell, V Harvey, C S Malcolm, R H Porter.   

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Year:  2000        PMID： 10956184     DOI： 10.1021/jm990945v

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  5 in total

1.  Selective acetylcholinesterase inhibitor activated by acetylcholinesterase releases an active chelator with neurorescuing and anti-amyloid activities.

Authors:  Hailin Zheng; Moussa B H Youdim; Mati Fridkin
Journal:  ACS Chem Neurosci       Date:  2010-10-04       Impact factor: 4.418

2.  Minding metals: tailoring multifunctional chelating agents for neurodegenerative disease.

Authors:  Lissette R Perez; Katherine J Franz
Journal:  Dalton Trans       Date:  2009-12-17       Impact factor: 4.390

Review 3.  Mechanistic Insights of Chelator Complexes with Essential Transition Metals: Antioxidant/Pro-Oxidant Activity and Applications in Medicine.

Authors:  Viktor A Timoshnikov; Olga Yu Selyutina; Nikolay E Polyakov; Victoria Didichenko; George J Kontoghiorghes
Journal:  Int J Mol Sci       Date:  2022-01-23       Impact factor: 5.923

4.  Synthesis, physicochemical characterization and neuroprotective evaluation of novel 1-hydroxypyrazin-2(1H)-one iron chelators in an in vitro cell model of Parkinson's disease.

Authors:  Frank W Lewis; Kathleen Bird; Jean-Philippe Navarro; Rawa El Fallah; Jeremy Brandel; Véronique Hubscher-Bruder; Andrew Tsatsanis; James A Duce; David Tétard; Samuel Bourne; Mahmoud Maina; Ilse S Pienaar
Journal:  Dalton Trans       Date:  2022-03-01       Impact factor: 4.390

5.  Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer's Disease.

Authors:  Angel Agis-Torres; Monica Sölhuber; Maria Fernandez; J M Sanchez-Montero
Journal:  Curr Neuropharmacol       Date:  2014-01       Impact factor: 7.363
  5 in total

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