Literature DB >> 10955854

Carrier-mediated transport of macrolide antimicrobial agents across Caco-2 cell monolayers.

H Saito1, Y Fukasawa, Y Otsubo, K Yamada, H Sezaki, S Yamashita.   

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Year:  2000        PMID： 10955854     DOI： 10.1023/a:1007550820196

Source DB:  PubMed          Journal:  Pharm Res        ISSN： 0724-8741            Impact factor:   4.200


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  17 in total

1.  Chemical modification of erythromycins. VI. Structure and antibacterial activity of acid degradation products of 6-O-methylerythromycins A.

Authors:  S Morimoto; Y Misawa; T Asaka; H Kondoh; Y Watanabe
Journal:  J Antibiot (Tokyo)       Date:  1990-05       Impact factor: 2.649

2.  Development of Caco-2 cells expressing high levels of cDNA-derived cytochrome P4503A4.

Authors:  C L Crespi; B W Penman; M Hu
Journal:  Pharm Res       Date:  1996-11       Impact factor: 4.200

3.  In vitro analysis of the activity of the major human hepatic CYP enzyme (CYP3A4) using [N-methyl-14C]-erythromycin.

Authors:  R J Riley; D Howbrook
Journal:  J Pharmacol Toxicol Methods       Date:  1997-12       Impact factor: 1.950

4.  Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells.

Authors:  P Artursson; J Karlsson
Journal:  Biochem Biophys Res Commun       Date:  1991-03-29       Impact factor: 3.575

Review 5.  Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

Authors:  V J Wacher; C Y Wu; L Z Benet
Journal:  Mol Carcinog       Date:  1995-07       Impact factor: 4.784

6.  Evaluation of the intestinal absorption of erythromycin in man: absolute bioavailability and comparison with enteric coated erythromycin.

Authors:  A A Somogyi; F Bochner; D Hetzel; D B Williams
Journal:  Pharm Res       Date:  1995-01       Impact factor: 4.200

7.  Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators.

Authors:  J Hunter; M A Jepson; T Tsuruo; N L Simmons; B H Hirst
Journal:  J Biol Chem       Date:  1993-07-15       Impact factor: 5.157

8.  Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein.

Authors:  H Wakasugi; I Yano; T Ito; T Hashida; T Futami; R Nohara; S Sasayama; K Inui
Journal:  Clin Pharmacol Ther       Date:  1998-07       Impact factor: 6.875

9.  Possible involvement of multiple P-glycoprotein-mediated efflux systems in the transport of verapamil and other organic cations across rat intestine.

Authors:  H Saitoh; B J Aungst
Journal:  Pharm Res       Date:  1995-09       Impact factor: 4.200

10.  Biochemical characterization of resistance to mitoxantrone and adriamycin in Caco-2 human colon adenocarcinoma cells: a possible role for glutathione S-transferases.

Authors:  W H Peters; H M Roelofs
Journal:  Cancer Res       Date:  1992-04-01       Impact factor: 12.701
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  5 in total

Review 1.  Interethnic differences in pharmacokinetics of antibacterials.

Authors:  Danny Tsai; Janattul-Ain Jamal; Joshua S Davis; Jeffrey Lipman; Jason A Roberts
Journal:  Clin Pharmacokinet       Date:  2015-03       Impact factor: 6.447

2.  Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug-Drug Interactions and Co-medication Regimens.

Authors:  Daniel Moj; Nina Hanke; Hannah Britz; Sebastian Frechen; Tobias Kanacher; Thomas Wendl; Walter Emil Haefeli; Thorsten Lehr
Journal:  AAPS J       Date:  2016-11-07       Impact factor: 4.009

3.  Influence of P-glycoprotein inhibitors on accumulation of macrolides in J774 murine macrophages.

Authors:  Cristina Seral; Jean-Michel Michot; Hugues Chanteux; Marie-Paule Mingeot-Leclercq; Paul M Tulkens; Françoise Van Bambeke
Journal:  Antimicrob Agents Chemother       Date:  2003-03       Impact factor: 5.191

4.  Roles of P-glycoprotein, Bcrp, and Mrp2 in biliary excretion of spiramycin in mice.

Authors:  Xianbin Tian; Jun Li; Maciej J Zamek-Gliszczynski; Arlene S Bridges; Peijin Zhang; Nita J Patel; Thomas J Raub; Gary M Pollack; Kim L R Brouwer
Journal:  Antimicrob Agents Chemother       Date:  2007-06-18       Impact factor: 5.191

5.  A quantitative systems pharmacology approach, incorporating a novel liver model, for predicting pharmacokinetic drug-drug interactions.

Authors:  Mohammed H Cherkaoui-Rbati; Stuart W Paine; Peter Littlewood; Cyril Rauch
Journal:  PLoS One       Date:  2017-09-14       Impact factor: 3.240
  5 in total

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