Literature DB >> 10953969

Cellular and molecular aspects of human CD34+ CD38- precursors: analysis of a primitive hematopoietic population.

M Xiao1, D C Dooley.   

Abstract

Hematopoiesis is a complex, highly regulated process in which a small number of primitive stem cells produce all the mature blood and immune cells required by an animal throughout its life. In this review, we summarize current understanding of human CD34+ CD38- cells, a small subclass of hematopoietic cells, which is enriched for primitive precursors, including stem cells. This review emphasizes functional, molecular and immunophenotypic characteristics of the cells and includes some of the factors which are believed to regulate the survival, growth and differentiation of this important class of cells.

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Year:  2000        PMID： 10953969     DOI： 10.3109/10428190009059267

Source DB:  PubMed          Journal:  Leuk Lymphoma        ISSN： 1026-8022


  11 in total

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2.  Identification of the ectoenzyme CD38 as a marker of committed preadipocytes.

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Journal:  Int J Obes (Lond)       Date:  2017-06-14       Impact factor: 5.095

3.  Detection of human hematopoietic stem cell engraftment in the livers of adult immunodeficient mice by an optimized flow cytometric method.

Authors:  Nicole L Varga; Alicia Bárcena; Marina E Fomin; Marcus O Muench
Journal:  Stem Cell Stud       Date:  2010-11-23

4.  Retinoid-regulated FGF8f secretion by osteoblasts bypasses retinoid stimuli to mediate granulocytic differentiation of myeloid leukemia cells.

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5.  Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging.

Authors:  Claudia E Rübe; Andreas Fricke; Thomas A Widmann; Tobias Fürst; Henning Madry; Michael Pfreundschuh; Christian Rübe
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6.  Distinct clinical and experimental characteristics in the patients younger than 60 years old with myelodysplastic syndromes.

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7.  Isolation, growth and identification of colony-forming cells with erythroid, myeloid, dendritic cell and NK-cell potential from human fetal liver.

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8.  Correlation of umbilical cord blood haematopoietic stem and progenitor cell levels with birth weight: implications for a prenatal influence on cancer risk.

Authors:  W C Strohsnitter; T M Savarese; H P Low; D P Chelmow; P Lagiou; M Lambe; K Edmiston; Q Liu; I Baik; K L Noller; H-O Adami; D Trichopoulos; C-C Hsieh
Journal:  Br J Cancer       Date:  2008-02-05       Impact factor: 7.640

9.  Establishment and validation of an updated diagnostic FCM scoring system based on pooled immunophenotyping in CD34+ blasts and its clinical significance for myelodysplastic syndromes.

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Journal:  PLoS One       Date:  2014-02-18       Impact factor: 3.240

10.  The adult livers of immunodeficient mice support human hematopoiesis: evidence for a hepatic mast cell population that develops early in human ontogeny.

Authors:  Marcus O Muench; Ashley I Beyer; Marina E Fomin; Rahul Thakker; Usha S Mulvaney; Masato Nakamura; Hiroshi Suemizu; Alicia Bárcena
Journal:  PLoS One       Date:  2014-05-12       Impact factor: 3.240
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