Literature DB >> 10953096

Follicular dendritic cells in TSE pathogenesis.

M E Bruce1, K L Brown, N A Mabbott, C F Farquhar, M Jeffrey.   

Abstract

The pathogenesis of transmissible spongiform encephalopathies (TSEs) often includes a replication phase in lymphoid tissues before infection spreads to the central nervous system. Recent studies show that the follicular dendritic cells of the germinal centres are critical for this replication. These cells are therefore potential targets for therapy or prophylaxis in natural TSEs, such as variant Creutzfeldt-Jakob disease.

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Year:  2000        PMID： 10953096     DOI： 10.1016/s0167-5699(00)01696-0

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  13 in total

1.  Neuroinvasion by a Creutzfeldt-Jakob disease agent in the absence of B cells and follicular dendritic cells.

Authors:  M J Shlomchik; K Radebold; N Duclos; L Manuelidis
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-24       Impact factor: 11.205

2.  Autonomic nervous system innervation of lymphoid territories in spleen: a possible involvement of noradrenergic neurons for prion neuroinvasion in natural scrapie.

Authors:  A Bencsik; S Lezmi; T Baron
Journal:  J Neurovirol       Date:  2001-10       Impact factor: 2.643

Review 3.  Prion diseases: current understanding of epidemiology and pathogenesis, and therapeutic advances.

Authors:  Maria Caramelli; Giuseppe Ru; Pierluigi Acutis; Gianluigi Forloni
Journal:  CNS Drugs       Date:  2006       Impact factor: 5.749

4.  Genetic and environmental factors modify bovine spongiform encephalopathy incubation period in mice.

Authors:  K Manolakou; J Beaton; I McConnell; C Farquar; J Manson; N D Hastie; M Bruce; I J Jackson
Journal:  Proc Natl Acad Sci U S A       Date:  2001-06-12       Impact factor: 11.205

5.  Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: evidence against dendritic cell involvement in neuroinvasion.

Authors:  Michael B A Oldstone; Richard Race; Diane Thomas; Hanna Lewicki; Dirk Homann; Sara Smelt; Andreas Holz; Pandelakis Koni; David Lo; Bruce Chesebro; Richard Flavell
Journal:  J Virol       Date:  2002-05       Impact factor: 5.103

6.  Scrapie affects the maturation cycle and immune complex trapping by follicular dendritic cells in mice.

Authors:  Gillian McGovern; Neil Mabbott; Martin Jeffrey
Journal:  PLoS One       Date:  2009-12-08       Impact factor: 3.240

7.  BSE infectivity in jejunum, ileum and ileocaecal junction of incubating cattle.

Authors:  Christine Hoffmann; Martin Eiden; Martin Kaatz; Markus Keller; Ute Ziegler; Ron Rogers; Bob Hills; Anne Balkema-Buschmann; Lucien van Keulen; Jorg G Jacobs; Martin H Groschup
Journal:  Vet Res       Date:  2011-02-07       Impact factor: 3.683

Review 8.  The diverse roles of mononuclear phagocytes in prion disease pathogenesis.

Authors:  Gwennaelle J Wathne; Neil A Mabbott
Journal:  Prion       Date:  2012-04-01       Impact factor: 3.931

9.  PrP expression, PrPSc accumulation and innervation of splenic compartments in sheep experimentally infected with scrapie.

Authors:  Randi Sørby; Lars Austbø; Charles McL Press; Grethe Skretting; Thor Landsverk; Arild Espenes
Journal:  PLoS One       Date:  2009-09-03       Impact factor: 3.240

10.  Test for detection of disease-associated prion aggregate in the blood of infected but asymptomatic animals.

Authors:  Binggong Chang; Xin Cheng; Shaoman Yin; Tao Pan; Hongtao Zhang; Poki Wong; Shin-Chung Kang; Fan Xiao; Huimin Yan; Chaoyang Li; Lisa L Wolfe; Michael W Miller; Thomas Wisniewski; Mark I Greene; Man-Sun Sy
Journal:  Clin Vaccine Immunol       Date:  2006-11-01
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