Literature DB >> 1095283

Fenmetozole in acute alcholol intoxication in man.

H B McNamee, J H Mendelson, J Korn.   

Abstract

Forty healthy adult male volunteers were studied to determine the efficacy of fenmetozole to antagonize the effects of acute alcholol intoxication. Twenty subjects receive placebo and 20 fenmetozole in dosage of 100 mg and 200 mg in a double-blind paradigm. Pretreatment with fenmetozole failed to antogonize or attenuate cognitive, perceptual, motor and affective changes associated with acute alchol intoxication.

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Year:  1975        PMID: 1095283     DOI: 10.1002/cpt1975176735

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN: 0009-9236            Impact factor:   6.875


  1 in total

1.  An evaluation of the selectivity of fenmetozole (DH-524) reversal of ethanol-induced changes in central nervous system function.

Authors:  G D Frye; G R Breese; R B Mailman; R A Vogel; M G Ondrusek; R A Mueller
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530

  1 in total

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