| Literature DB >> 10950469 |
S Angus1, J Sugars, R Boltezar, S Koskewich, N M Schneider.
Abstract
An 18-week, double-blind, crossover study of amantadine and neuroleptics in the treatment of tardive dyskinesia (TD) is described. A fixed-dose regimen was used, and objective rating scales for TD, extrapyramidal symptoms, and mental state were employed. The results indicate that amantadine is significantly better than placebo in the management of TD and that there is little risk of exacerbating psychosis. Further investigation of this potentially useful medication is warranted.Entities:
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Year: 1997 PMID： 10950469 DOI： 10.1097/00004714-199704000-00004
Source DB: PubMed Journal: J Clin Psychopharmacol ISSN： 0271-0749 Impact factor: 3.153