Literature DB >> 1094945

Comparative effect of tetracycline and doxycycline on the occurrence of resistant Escherichia coli in the fecal flora.

J G Bartlett, L A Bustetter, S L Gorbach, A B Onderdonk.   

Abstract

Antibiotic-induced changes in the fecal microflora after oral administration of tetracycline hydrochloride and doxycycline for 8 to 10 days were compared. A significant difference was noted in the concentrations of Escherichia coli resistant to tetracyclines. With tetracycline hydrochloride, there was a mean increase of approximately 10(4) resistant strains per g compared to only 10(1)/g for doxycycline. This difference is ascribed to reduced intestinal concentrations of bioactive drug with recommended oral dosage for doxycycline.

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Year:  1975        PMID： 1094945      PMCID： PMC429072          DOI： 10.1128/AAC.7.1.55

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  Distribution and excretion of four tetracycline analogues in normal young men.

Authors:  C M KUNIN; A C DORNBUSH; M FINLAND
Journal:  J Clin Invest       Date:  1959-11       Impact factor: 14.808

2.  The effect of terramycin on the intestinal bacterial flora of patients being prepared for intestinal surgery.

Authors:  W H DEARING; G M NEEDHAM
Journal:  Proc Staff Meet Mayo Clin       Date:  1951-01-31

3.  The effect of aureomycin on the bacterial flora of the intestinal tract of man; a contribution to preoperative preparation.

Authors:  W H DEARING; F R HEILMAN
Journal:  Proc Staff Meet Mayo Clin       Date:  1950-02-15

4.  [Tetracycline kinetics in man. Digestive absorption and serum concentration].

Authors:  J Fabre; E Milek; P Kalfopoulos; G Mérier
Journal:  Schweiz Med Wochenschr       Date:  1971-05-01

5.  The effect of oral tetracycline HCl and doxycycline on the intestinal flora.

Authors:  N A Hinton
Journal:  Curr Ther Res Clin Exp       Date:  1970-06

6.  The disposition of doxycyline by man and dog.

Authors:  M Schach von Wittenau; T M Twomey
Journal:  Chemotherapy       Date:  1971       Impact factor: 2.544

7.  Effect of oral tetracycline on the occurrence of tetracycline-resistant strains of Escherichia coli in the intestinal tract of humans.

Authors:  D C Hirsh; G C Burton; D C Blenden
Journal:  Antimicrob Agents Chemother       Date:  1973-07       Impact factor: 5.191
  7 in total
  6 in total

1.  Serogrouping and antibiotic resistance of Escherichia coli isolated from broiler chicken with colibacillosis in center of Algeria.

Authors:  Zehor Halfaoui; Nabil Mohamed Menoueri; Lyes Mohamed Bendali
Journal:  Vet World       Date:  2017-07-28

2.  Microbiological Profile of Sarecycline, a Novel Targeted Spectrum Tetracycline for the Treatment of Acne Vulgaris.

Authors:  George Zhanel; Ian Critchley; Lynn-Yao Lin; Nancy Alvandi
Journal:  Antimicrob Agents Chemother       Date:  2018-12-21       Impact factor: 5.191

Review 3.  Sarecycline: a narrow spectrum tetracycline for the treatment of moderate-to-severe acne vulgaris.

Authors:  Angela Yen Moore; Jean Elizze M Charles; Stephen Moore
Journal:  Future Microbiol       Date:  2019-09-02       Impact factor: 3.165

Review 4.  Antibacterial Mechanisms and Efficacy of Sarecycline in Animal Models of Infection and Inflammation.

Authors:  Christopher G Bunick; Jonette Keri; S Ken Tanaka; Nika Furey; Giovanni Damiani; Jodi L Johnson; Ayman Grada
Journal:  Antibiotics (Basel)       Date:  2021-04-15

5.  Multidrug-resistant gram-negative bacteria colonization of healthy US military personnel in the US and Afghanistan.

Authors:  Todd J Vento; David W Cole; Katrin Mende; Tatjana P Calvano; Elizabeth A Rini; Charla C Tully; Wendy C Zera; Charles H Guymon; Xin Yu; Kristelle A Cheatle; Kevin S Akers; Miriam L Beckius; Michael L Landrum; Clinton K Murray
Journal:  BMC Infect Dis       Date:  2013-02-05       Impact factor: 3.090

6.  Mitochondria as oncotarget: a comparison between the tetracycline analogs doxycycline and COL-3.

Authors:  Margherita Protasoni; Albert M Kroon; Jan-Willem Taanman
Journal:  Oncotarget       Date:  2018-09-18
  6 in total

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