Literature DB >> 10948442

The molecular and cellular biology of HER2/neu gene amplification/overexpression and the clinical development of herceptin (trastuzumab) therapy for breast cancer.

M D Pegram1, G Konecny, D J Slamon.   

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Year:  2000        PMID: 10948442     DOI: 10.1007/978-1-4757-3147-7_4

Source DB:  PubMed          Journal:  Cancer Treat Res        ISSN: 0927-3042


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4.  Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab.

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5.  Robust unmixing of tumor states in array comparative genomic hybridization data.

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6.  TIMP-1 and VEGF-165 serum concentration during first-line therapy of ovarian cancer patients.

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7.  Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial.

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Review 8.  Unlocking the power of cross-species genomic analyses: identification of evolutionarily conserved breast cancer networks and validation of preclinical models.

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Journal:  Breast Cancer Res       Date:  2008-09-11       Impact factor: 6.466

9.  Applying unmixing to gene expression data for tumor phylogeny inference.

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10.  HER-2/neu oncogene amplification by chromogenic in situ hybridization in 130 breast cancers using tissue microarray and clinical follow-up studies.

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