Literature DB >> 10948183

Analysis of genes expressed at the infective larval stage validates utility of Litomosoides sigmodontis as a murine model for filarial vaccine development.

J E Allen1, J Daub, D Guiliano, A McDonnell, M Lizotte-Waniewski, D W Taylor, M Blaxter.   

Abstract

We used an expressed sequence tag approach to analyze genes expressed by the infective larvae of the rodent filarial parasite Litomosoides sigmodontis. One hundred fifty two new genes were identified, including several proposed as vaccine candidates in studies with human filarial parasites. Our findings have important implications for the use of L. sigmodontis as a model for filarial infection.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 10948183      PMCID： PMC101817          DOI： 10.1128/IAI.68.9.5454-5458.2000

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  27 in total

1.  Acanthocheilonema viteae: characterization of a molt-associated excretory/secretory 18-kDa protein.

Authors:  T Pogonka; U Oberländer; T Marti; R Lucius
Journal:  Exp Parasitol       Date:  1999-10       Impact factor: 2.011

2.  A unified nomenclature for filarial genes.

Authors:  M L Blaxter; D B Guiliano; A L Scott; S A Williams
Journal:  Parasitol Today       Date:  1997-11

3.  Hookworm burden reductions in BALB/c mice vaccinated with recombinant Ancylostoma secreted proteins (ASPs) from Ancylostoma duodenale, Ancylostoma caninum and Necator americanus.

Authors:  L Sen; K Ghosh; Z Bin; S Qiang; M G Thompson; J M Hawdon; R A Koski; X Shuhua; P J Hotez
Journal:  Vaccine       Date:  2000-01-06       Impact factor: 3.641

4.  Differentially expressed, abundant trans-spliced cDNAs from larval Brugia malayi.

Authors:  W F Gregory; M L Blaxter; R M Maizels
Journal:  Mol Biochem Parasitol       Date:  1997-07       Impact factor: 1.759

5.  The abundant larval transcript-1 and -2 genes of Brugia malayi encode stage-specific candidate vaccine antigens for filariasis.

Authors:  W F Gregory; A K Atmadja; J E Allen; R M Maizels
Journal:  Infect Immun       Date:  2000-07       Impact factor: 3.441

6.  An immunogenic Onchocerca volvulus antigen: a specific and early marker of infection.

Authors:  E Lobos; N Weiss; M Karam; H R Taylor; E A Ottesen; T B Nutman
Journal:  Science       Date:  1991-03-29       Impact factor: 47.728

7.  The Wuchereria bancrofti orthologue of Brugia malayi SXP1 and the diagnosis of bancroftian filariasis.

Authors:  K V Rao; M Eswaran; V Ravi; B Gnanasekhar; R B Narayanan; P Kaliraj; K Jayaraman; A Marson; N Raghavan; A L Scott
Journal:  Mol Biochem Parasitol       Date:  2000-03-15       Impact factor: 1.759

8.  A survey of genes expressed in adults of the human hookworm, Necator americanus.

Authors:  J Daub; A Loukas; D I Pritchard; M Blaxter
Journal:  Parasitology       Date:  2000-02       Impact factor: 3.234

9.  Purification and characterization of three larval excretory-secretory proteins of Dirofilaria immitis.

Authors:  G R Frank; R B Grieve
Journal:  Mol Biochem Parasitol       Date:  1996-01       Impact factor: 1.759

10.  Molecular cloning and characterization of onchocystatin, a cysteine proteinase inhibitor of Onchocerca volvulus.

Authors:  S Lustigman; B Brotman; T Huima; A M Prince; J H McKerrow
Journal:  J Biol Chem       Date:  1992-08-25       Impact factor: 5.157
View more
  15 in total

Review 1.  Immunology of parasitic helminth infections.

Authors:  Andrew S MacDonald; Maria Ilma Araujo; Edward J Pearce
Journal:  Infect Immun       Date:  2002-02       Impact factor: 3.441

2.  Comparative analysis of the secretome from a model filarial nematode (Litomosoides sigmodontis) reveals maximal diversity in gravid female parasites.

Authors:  Stuart D Armstrong; Simon A Babayan; Nathaly Lhermitte-Vallarino; Nick Gray; Dong Xia; Coralie Martin; Sujai Kumar; David W Taylor; Mark L Blaxter; Jonathan M Wastling; Benjamin L Makepeace
Journal:  Mol Cell Proteomics       Date:  2014-06-23       Impact factor: 5.911

3.  Molecular characterization and evaluation of Onchocerca volvulus-secreted larval acidic protein 1 (SLAP1) as a putative vaccine candidate on endemic population of lymphatic filariasis.

Authors:  Natarajan Mahalakshmi; Ramanathan Aparnaa; Lawrance Ansel Vishal; Perumal Kaliraj
Journal:  Parasitol Res       Date:  2013-07-05       Impact factor: 2.289

4.  Crucial epitopes of Wuchereria bancrofti abundant larval transcript recognized in natural infection.

Authors:  J Madhumathi; D Pradiba; P R Prince; P J Jeyaprita; D N Rao; P Kaliraj
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2010-08-29       Impact factor: 3.267

5.  Increased early local immune responses and altered worm development in high-dose infections of mice susceptible to the filaria Litomosoides sigmodontis.

Authors:  Simon Babayan; Tarik Attout; Sabine Specht; Achim Hoerauf; Georges Snounou; Laurent Rénia; Masataka Korenaga; Odile Bain; Coralie Martin
Journal:  Med Microbiol Immunol       Date:  2004-08-26       Impact factor: 3.402

6.  Screening of different classes of proteases in microfilarial and adult stages of Setaria cervi.

Authors:  Daya Ram Pokharel; Elesela Srikanth; Sushma Rathaur
Journal:  Parasitol Res       Date:  2009-01-29       Impact factor: 2.289

7.  Resistance and susceptibility to filarial infection with Litomosoides sigmodontis are associated with early differences in parasite development and in localized immune reactions.

Authors:  Simon Babayan; Marie-Noëlle Ungeheuer; Coralie Martin; Tarik Attout; Elodie Belnoue; Georges Snounou; Laurent Rénia; Masataka Korenaga; Odile Bain
Journal:  Infect Immun       Date:  2003-12       Impact factor: 3.441

8.  Deletion of parasite immune modulatory sequences combined with immune activating signals enhances vaccine mediated protection against filarial nematodes.

Authors:  Simon A Babayan; Honglin Luo; Nick Gray; David W Taylor; Judith E Allen
Journal:  PLoS Negl Trop Dis       Date:  2012-12-27

9.  Brugia malayi excreted/secreted proteins at the host/parasite interface: stage- and gender-specific proteomic profiling.

Authors:  Sasisekhar Bennuru; Roshanak Semnani; Zhaojing Meng; Jose M C Ribeiro; Timothy D Veenstra; Thomas B Nutman
Journal:  PLoS Negl Trop Dis       Date:  2009-04-07

10.  Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensis and the evolution of secreted proteins in parasites.

Authors:  Yvonne M Harcus; John Parkinson; Cecilia Fernández; Jennifer Daub; Murray E Selkirk; Mark L Blaxter; Rick M Maizels
Journal:  Genome Biol       Date:  2004-05-18       Impact factor: 13.583
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.