Literature DB >> 10946236

The BRCA1 C-terminal domain: structure and function.

T Huyton1, P A Bates, X Zhang, M J Sternberg, P S Freemont.   

Abstract

The BRCA1 C-terminal region contains a duplicated globular domain termed BRCT that is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo/hetero BRCT multimers, BRCT-non-BRCT interactions, and interactions with DNA strand breaks. The sequence and functional diversity of the BRCT superfamily suggests that BRCT domains are evolutionarily convenient interaction modules.

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Year:  2000        PMID： 10946236     DOI： 10.1016/s0921-8777(00)00034-3

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  42 in total

1.  Primary microcephaly: microcephalin and ASPM determine the size of the human brain.

Authors:  Arun Kumar; M Markandaya; S C Girimaji
Journal:  J Biosci       Date:  2002-12       Impact factor: 1.826

2.  Ten members of the Arabidopsis gene family encoding methyl-CpG-binding domain proteins are transcriptionally active and at least one, AtMBD11, is crucial for normal development.

Authors:  Anita Berg; Trine J Meza; Mirela Mahić; Tage Thorstensen; Kjetil Kristiansen; Reidunn B Aalen
Journal:  Nucleic Acids Res       Date:  2003-09-15       Impact factor: 16.971

3.  Comparison of BRCT domains of BRCA1 and 53BP1: a biophysical analysis.

Authors:  Caroline M S Ekblad; Assaf Friedler; Dmitry Veprintsev; Richard L Weinberg; Laura S Itzhaki
Journal:  Protein Sci       Date:  2004-03       Impact factor: 6.725

4.  TopBP1 contains a transcriptional activation domain suppressed by two adjacent BRCT domains.

Authors:  Roni H G Wright; Edward S Dornan; Mary M Donaldson; Iain M Morgan
Journal:  Biochem J       Date:  2006-12-15       Impact factor: 3.857

Review 5.  Y-family DNA polymerases in mammalian cells.

Authors:  Caixia Guo; J Nicole Kosarek-Stancel; Tie-Shan Tang; Errol C Friedberg
Journal:  Cell Mol Life Sci       Date:  2009-04-15       Impact factor: 9.261

6.  Evidence for a structural relationship between BRCT domains and the helicase domains of the replication initiators encoded by the Polyomaviridae and Papillomaviridae families of DNA tumor viruses.

Authors:  Anuradha Kumar; Woo S Joo; Gretchen Meinke; Stephanie Moine; Elena N Naumova; Peter A Bullock
Journal:  J Virol       Date:  2008-06-25       Impact factor: 5.103

7.  Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

Authors:  Timothy R Rebbeck; Nandita Mitra; Fei Wan; Olga M Sinilnikova; Sue Healey; Lesley McGuffog; Sylvie Mazoyer; Georgia Chenevix-Trench; Douglas F Easton; Antonis C Antoniou; Katherine L Nathanson; Yael Laitman; Anya Kushnir; Shani Paluch-Shimon; Raanan Berger; Jamal Zidan; Eitan Friedman; Hans Ehrencrona; Marie Stenmark-Askmalm; Zakaria Einbeigi; Niklas Loman; Katja Harbst; Johanna Rantala; Beatrice Melin; Dezheng Huo; Olufunmilayo I Olopade; Joyce Seldon; Patricia A Ganz; Robert L Nussbaum; Salina B Chan; Kunle Odunsi; Simon A Gayther; Susan M Domchek; Banu K Arun; Karen H Lu; Gillian Mitchell; Beth Y Karlan; Christine Walsh; Jenny Lester; Andrew K Godwin; Harsh Pathak; Eric Ross; Mary B Daly; Alice S Whittemore; Esther M John; Alexander Miron; Mary Beth Terry; Wendy K Chung; David E Goldgar; Saundra S Buys; Ramunas Janavicius; Laima Tihomirova; Nadine Tung; Cecilia M Dorfling; Elizabeth J van Rensburg; Linda Steele; Susan L Neuhausen; Yuan Chun Ding; Bent Ejlertsen; Anne-Marie Gerdes; Thomas v O Hansen; Teresa Ramón y Cajal; Ana Osorio; Javier Benitez; Javier Godino; Maria-Isabel Tejada; Mercedes Duran; Jeffrey N Weitzel; Kristie A Bobolis; Sharon R Sand; Annette Fontaine; Antonella Savarese; Barbara Pasini; Bernard Peissel; Bernardo Bonanni; Daniela Zaffaroni; Francesca Vignolo-Lutati; Giulietta Scuvera; Giuseppe Giannini; Loris Bernard; Maurizio Genuardi; Paolo Radice; Riccardo Dolcetti; Siranoush Manoukian; Valeria Pensotti; Viviana Gismondi; Drakoulis Yannoukakos; Florentia Fostira; Judy Garber; Diana Torres; Muhammad Usman Rashid; Ute Hamann; Susan Peock; Debra Frost; Radka Platte; D Gareth Evans; Rosalind Eeles; Rosemarie Davidson; Diana Eccles; Trevor Cole; Jackie Cook; Carole Brewer; Shirley Hodgson; Patrick J Morrison; Lisa Walker; Mary E Porteous; M John Kennedy; Louise Izatt; Julian Adlard; Alan Donaldson; Steve Ellis; Priyanka Sharma; Rita Katharina Schmutzler; Barbara Wappenschmidt; Alexandra Becker; Kerstin Rhiem; Eric Hahnen; Christoph Engel; Alfons Meindl; Stefanie Engert; Nina Ditsch; Norbert Arnold; Hans Jörg Plendl; Christoph Mundhenke; Dieter Niederacher; Markus Fleisch; Christian Sutter; C R Bartram; Nicola Dikow; Shan Wang-Gohrke; Dorothea Gadzicki; Doris Steinemann; Karin Kast; Marit Beer; Raymonda Varon-Mateeva; Andrea Gehrig; Bernhard H Weber; Dominique Stoppa-Lyonnet; Olga M Sinilnikova; Sylvie Mazoyer; Claude Houdayer; Muriel Belotti; Marion Gauthier-Villars; Francesca Damiola; Nadia Boutry-Kryza; Christine Lasset; Hagay Sobol; Jean-Philippe Peyrat; Danièle Muller; Jean-Pierre Fricker; Marie-Agnès Collonge-Rame; Isabelle Mortemousque; Catherine Nogues; Etienne Rouleau; Claudine Isaacs; Anne De Paepe; Bruce Poppe; Kathleen Claes; Kim De Leeneer; Marion Piedmonte; Gustavo Rodriguez; Katie Wakely; John Boggess; Stephanie V Blank; Jack Basil; Masoud Azodi; Kelly-Anne Phillips; Trinidad Caldes; Miguel de la Hoya; Atocha Romero; Heli Nevanlinna; Kristiina Aittomäki; Annemarie H van der Hout; Frans B L Hogervorst; Senno Verhoef; J Margriet Collée; Caroline Seynaeve; Jan C Oosterwijk; Johannes J P Gille; Juul T Wijnen; Encarna B Gómez Garcia; Carolien M Kets; Margreet G E M Ausems; Cora M Aalfs; Peter Devilee; Arjen R Mensenkamp; Ava Kwong; Edith Olah; Janos Papp; Orland Diez; Conxi Lazaro; Esther Darder; Ignacio Blanco; Mónica Salinas; Anna Jakubowska; Jan Lubinski; Jacek Gronwald; Katarzyna Jaworska-Bieniek; Katarzyna Durda; Grzegorz Sukiennicki; Tomasz Huzarski; Tomasz Byrski; Cezary Cybulski; Aleksandra Toloczko-Grabarek; Elżbieta Złowocka-Perłowska; Janusz Menkiszak; Adalgeir Arason; Rosa B Barkardottir; Jacques Simard; Rachel Laframboise; Marco Montagna; Simona Agata; Elisa Alducci; Ana Peixoto; Manuel R Teixeira; Amanda B Spurdle; Min Hyuk Lee; Sue K Park; Sung-Won Kim; Tara M Friebel; Fergus J Couch; Noralane M Lindor; Vernon S Pankratz; Lucia Guidugli; Xianshu Wang; Marc Tischkowitz; Lenka Foretova; Joseph Vijai; Kenneth Offit; Mark Robson; Rohini Rau-Murthy; Noah Kauff; Anneliese Fink-Retter; Christian F Singer; Christine Rappaport; Daphne Gschwantler-Kaulich; Georg Pfeiler; Muy-Kheng Tea; Andreas Berger; Mark H Greene; Phuong L Mai; Evgeny N Imyanitov; Amanda Ewart Toland; Leigha Senter; Anders Bojesen; Inge Sokilde Pedersen; Anne-Bine Skytte; Lone Sunde; Mads Thomassen; Sanne Traasdahl Moeller; Torben A Kruse; Uffe Birk Jensen; Maria Adelaide Caligo; Paolo Aretini; Soo-Hwang Teo; Christina G Selkirk; Peter J Hulick; Irene Andrulis
Journal:  JAMA       Date:  2015-04-07       Impact factor: 56.272

Review 8.  BRCA1--conductor of the breast stem cell orchestra: the role of BRCA1 in mammary gland development and identification of cell of origin of BRCA1 mutant breast cancer.

Authors:  Niamh E Buckley; Paul B Mullan
Journal:  Stem Cell Rev Rep       Date:  2012-09       Impact factor: 5.739

9.  Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1.

Authors:  Yang Shen; Liang Tong
Journal:  Biochemistry       Date:  2008-05-02       Impact factor: 3.162

10.  Establishment of a mouse model with misregulated chromosome condensation due to defective Mcph1 function.

Authors:  Marc Trimborn; Mahdi Ghani; Diego J Walther; Monika Dopatka; Véronique Dutrannoy; Andreas Busche; Franziska Meyer; Stefanie Nowak; Jean Nowak; Claus Zabel; Joachim Klose; Veronica Esquitino; Masoud Garshasbi; Andreas W Kuss; Hans-Hilger Ropers; Susanne Mueller; Charlotte Poehlmann; Ioannis Gavvovidis; Detlev Schindler; Karl Sperling; Heidemarie Neitzel
Journal:  PLoS One       Date:  2010-02-16       Impact factor: 3.240
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