Literature DB >> 10945128

Clinical observations of the treatment of canine perianal fistulas with topical tacrolimus in 10 dogs.

B S Misseghers1, A G Binnington, K A Mathews.   

Abstract

Tacrolimus ointment, a potent immunosuppressive medication, was evaluated for efficacy in the treatment of perianal fistulas in dogs. Ten dogs with perianal fistulas were treated with topical tacrolimus ointment once to twice daily for 16 weeks. Full healing of the fistulas occurred in 50% and was noticeably improved in 90% of dogs.

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Year:  2000        PMID： 10945128      PMCID： PMC1476229     

Source DB:  PubMed          Journal:  Can Vet J        ISSN： 0008-5286            Impact factor:   1.008


  11 in total

1.  Topical immunosuppression in skin grafting with FK 506 ointment.

Authors:  K Yuzawa; H Taniguchi; K Seino; M Otsuka; K Fukao
Journal:  Transplant Proc       Date:  1996-06       Impact factor: 1.066

2.  Association of perianal fistula and colitis in the German shepherd dog: response to high-dose prednisone and dietary therapy.

Authors:  K R Harkin; R Walshaw; T P Mullaney
Journal:  J Am Anim Hosp Assoc       Date:  1996 Nov-Dec       Impact factor: 1.023

3.  Randomized controlled trial of cyclosporine for treatment of perianal fistulas in dogs.

Authors:  K A Mathews; H R Sukhiani
Journal:  J Am Vet Med Assoc       Date:  1997-11-15       Impact factor: 1.936

4.  Cyclosporin treatment of perianal fistulas in dogs.

Authors:  K A Mathews; S A Ayres; C A Tano; S M Riley; H R Sukhiani; C Adams
Journal:  Can Vet J       Date:  1997-01       Impact factor: 1.008

Review 5.  Tacrolimus. An update of its pharmacology and clinical efficacy in the management of organ transplantation.

Authors:  C M Spencer; K L Goa; J C Gillis
Journal:  Drugs       Date:  1997-12       Impact factor: 9.546

Review 6.  Molecular mechanisms of immunosuppression by cyclosporins.

Authors:  G Zenke; G Baumann; R Wenger; P Hiestand; V Quesniaux; E Andersen; M H Schreier
Journal:  Ann N Y Acad Sci       Date:  1993-06-23       Impact factor: 5.691

7.  Bacterial population and histologic changes in dogs with perianal fistula.

Authors:  C R Killingsworth; R Walshaw; R W Dunstan; E J Rosser
Journal:  Am J Vet Res       Date:  1988-10       Impact factor: 1.156

Review 8.  The mechanism of action of FK-506 and cyclosporin A.

Authors:  G Wiederrecht; E Lam; S Hung; M Martin; N Sigal
Journal:  Ann N Y Acad Sci       Date:  1993-11-30       Impact factor: 5.691

Review 9.  The side-effects of ciclosporine-A and tacrolimus.

Authors:  M J Mihatsch; M Kyo; K Morozumi; Y Yamaguchi; V Nickeleit; B Ryffel
Journal:  Clin Nephrol       Date:  1998-06       Impact factor: 0.975

Review 10.  Action and toxicity of cyclosporine.

Authors:  W M Bennett; D J Norman
Journal:  Annu Rev Med       Date:  1986       Impact factor: 13.739
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