Literature DB >> 10941052

A Practical Asymmetric Synthesis of Enantiomerically Pure 3-Substituted Pyroglutamic Acids and Related Compounds This work was supported by grants from the U.S. Public Health Service (Grant DK 17420) and the National Institute of Drug Abuse (DA 06284 and DA 04248). The views expressed are those of the authors and not necessarily those of the USPHS.

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Abstract

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Year:  2000        PMID： 10941052

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  6 in total

1.  Michael addition reactions between chiral equivalents of a nucleophilic glycine and (S)- or (R)-3-[(E)-enoyl]-4-phenyl-1,3-oxazolidin-2-ones as a general method for efficient preparation of beta-substituted pyroglutamic acids. Case of topographically controlled stereoselectivity.

Authors:  Vadim A Soloshonok; Chaozhong Cai; Takeshi Yamada; Hisanori Ueki; Yasufumi Ohfune; Victor J Hruby
Journal:  J Am Chem Soc       Date:  2005-11-02       Impact factor: 15.419

2.  Enhanced stereoselectivity of a Cu(II) complex chiral auxiliary in the synthesis of Fmoc-L-γ-carboxyglutamic acid.

Authors:  Daniel J Smith; Glenn P A Yap; James A Kelley; Joel P Schneider
Journal:  J Org Chem       Date:  2011-02-03       Impact factor: 4.354

Review 3.  Organic chemistry and biology: chemical biology through the eyes of collaboration.

Authors:  Victor J Hruby
Journal:  J Org Chem       Date:  2009-12-18       Impact factor: 4.354

4.  Large-Scale Asymmetric Synthesis of Fmoc-(S)-2-Amino-6,6,6-Trifluorohexanoic Acid.

Authors:  Zizhen Yin; Hiroki Moriwaki; Hidenori Abe; Toshio Miwa; Jianlin Han; Vadim A Soloshonok
Journal:  ChemistryOpen       Date:  2019-06-07       Impact factor: 2.911

Review 5.  The Latest FDA-Approved Pharmaceuticals Containing Fragments of Tailor-Made Amino Acids and Fluorine.

Authors:  Qian Wang; Jianlin Han; Alexander Sorochinsky; Aitor Landa; Greg Butler; Vadim A Soloshonok
Journal:  Pharmaceuticals (Basel)       Date:  2022-08-14

6.  Design and synthesis of quasi-diastereomeric molecules with unchanging central, regenerating axial and switchable helical chirality via cleavage and formation of Ni(II)-O and Ni(II)-N coordination bonds.

Authors:  Vadim A Soloshonok; José Luis Aceña; Hisanori Ueki; Jianlin Han
Journal:  Beilstein J Org Chem       Date:  2012-11-13       Impact factor: 2.883
  6 in total

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