Literature DB >> 10940599

Salvia divinorum: an hallucinogenic mint which might become a new recreational drug in Switzerland.

C Giroud1, F Felber, M Augsburger, B Horisberger, L Rivier, P Mangin.   

Abstract

Salvia divinorum Epling & Jativa is an hallucinogenic mint traditionally used for curing and divination by the Mazatec Indians of Oaxaca, Mexico. Young people from Mexican cities were reported to smoke dried leaves of S. divinorum as a marijuana substitute. Recently, two S. divinorum specimens were seized in a large-scale illicit in-door and out-door hemp plantation. Salvinorin A also called divinorin A, a trans-neoclerodane diterpene, was identified in several organic solvent extracts by gas chromatography-mass spectrometry. The botanical identity of the plant was confirmed by comparing it to an authentic herbarium specimen. More plants were then discovered in Swiss horticulturists greenhouses. All these data taken together suggest that many attempts exist in Switzerland to use S. divinorum as a recreational drug. This phenomenon may be enhanced because neither the magic mint, nor its active compound are banned substances listed in the Swiss narcotic law.

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Year:  2000        PMID: 10940599     DOI: 10.1016/s0379-0738(00)00180-8

Source DB:  PubMed          Journal:  Forensic Sci Int        ISSN: 0379-0738            Impact factor:   2.395


  9 in total

1.  Evaluation of the transport, in vitro metabolism and pharmacokinetics of Salvinorin A, a potent hallucinogen.

Authors:  Zeynep S Teksin; Insong J Lee; Noble N Nemieboka; Ahmed A Othman; Vijay V Upreti; Hazem E Hassan; Shariq S Syed; Thomas E Prisinzano; Natalie D Eddington
Journal:  Eur J Pharm Biopharm       Date:  2009-06       Impact factor: 5.571

2.  Hallucinatory and rewarding effect of salvinorin A in zebrafish: kappa-opioid and CB1-cannabinoid receptor involvement.

Authors:  Daniela Braida; Valeria Limonta; Simona Pegorini; Alessia Zani; Chiara Guerini-Rocco; Enzo Gori; Mariaelvina Sala
Journal:  Psychopharmacology (Berl)       Date:  2007-01-12       Impact factor: 4.530

Review 3.  Neuropharmacology of the naturally occurring kappa-opioid hallucinogen salvinorin A.

Authors:  Christopher W Cunningham; Richard B Rothman; Thomas E Prisinzano
Journal:  Pharmacol Rev       Date:  2011-03-28       Impact factor: 25.468

4.  Kappa opioid mediation of cannabinoid effects of the potent hallucinogen, salvinorin A, in rodents.

Authors:  D Matthew Walentiny; Robert E Vann; Jonathan A Warner; Lindsey S King; Herbert H Seltzman; Hernán A Navarro; Charles E Twine; Brian F Thomas; Anne F Gilliam; Brian P Gilmour; F Ivy Carroll; Jenny L Wiley
Journal:  Psychopharmacology (Berl)       Date:  2010-03-31       Impact factor: 4.530

5.  Salvinicins A and B, new neoclerodane diterpenes from Salvia divinorum.

Authors:  Wayne W Harding; Kevin Tidgewell; Matthew Schmidt; Kushal Shah; Christina M Dersch; John Snyder; Damon Parrish; Jeffrey R Deschamps; Richard B Rothman; Thomas E Prisinzano
Journal:  Org Lett       Date:  2005-07-07       Impact factor: 6.005

6.  The plant-derived hallucinogen, salvinorin A, produces kappa-opioid agonist-like discriminative effects in rhesus monkeys.

Authors:  Eduardo R Butelman; Todd J Harris; Mary Jeanne Kreek
Journal:  Psychopharmacology (Berl)       Date:  2003-10-30       Impact factor: 4.530

7.  Salvinorin A: a potent naturally occurring nonnitrogenous kappa opioid selective agonist.

Authors:  Bryan L Roth; Karen Baner; Richard Westkaemper; Daniel Siebert; Kenner C Rice; SeAnna Steinberg; Paul Ernsberger; Richard B Rothman
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-21       Impact factor: 11.205

8.  Medicinal plants in the southern region of the State of Nuevo León, México.

Authors:  Eduardo Estrada-Castillón; Brianda Elizabeth Soto-Mata; Miriam Garza-López; José Ángel Villarreal-Quintanilla; Javier Jiménez-Pérez; Marisela Pando-Moreno; Jaime Sánchez-Salas; Laura Scott-Morales; Mauricio Cotera-Correa
Journal:  J Ethnobiol Ethnomed       Date:  2012-12-11       Impact factor: 2.733

9.  Recent national trends in Salvia divinorum use and substance-use disorders among recent and former Salvia divinorum users compared with nonusers.

Authors:  Li-Tzy Wu; George E Woody; Chongming Yang; Jih-Heng Li; Dan G Blazer
Journal:  Subst Abuse Rehabil       Date:  2011-04
  9 in total

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