Literature DB >> 10940376

Vasodilator effect of urotensin II, one of the most potent vasoconstricting factors, on rat coronary arteries.

Y Katano1, A Ishihata, T Aita, T Ogaki, T Horie.   

Abstract

The effects of human urotensin II on coronary flow were studied in the perfused rat heart. Urotensin II transiently decreased coronary flow, then induced sustained vasodilatation. In the presence of a cyclooxygenase inhibitor, diclofenac, coronary vasodilatation was significantly inhibited. A nitric oxide synthase inhibitor, N(G)-nitro-L-arginine (L-NNA), attenuated the urotensin-induced vasodilatation. These data suggest that urotensin II modulates coronary flow through factors such as cyclooxygenase products and nitric oxide to elicit coronary vasodilatation.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 10940376     DOI： 10.1016/s0014-2999(00)00506-9

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  14 in total

1.  Protein expression of urotensin II, urotensin-related peptide and their receptor in the lungs of patients with lymphangioleiomyomatosis.

Authors:  Arnold S Kristof; Zhipeng You; Yin-Shan Han; Adel Giaid
Journal:  Peptides       Date:  2010-04-28       Impact factor: 3.750

Review 2.  G Protein-coupled Receptor Biased Agonism.

Authors:  Sima Y Hodavance; Clarice Gareri; Rachel D Torok; Howard A Rockman
Journal:  J Cardiovasc Pharmacol       Date:  2016-03       Impact factor: 3.105

3.  Does cigarette smoking increase plasma urotensin II concentrations?

Authors:  S J Gold; J P Thompson; J P Williams; E E F Helm; J Sadler; W Song; L L Ng; D G Lambert
Journal:  Eur J Clin Pharmacol       Date:  2007-01-25       Impact factor: 2.953

4.  Cardiostimulant effects of urotensin-II in human heart in vitro.

Authors:  F D Russell; P Molenaar; D M O'Brien
Journal:  Br J Pharmacol       Date:  2001-01       Impact factor: 8.739

5.  Depressor and regionally-selective vasodilator effects of human and rat urotensin II in conscious rats.

Authors:  S M Gardiner; J E March; P A Kemp; A P Davenport; T Bennett
Journal:  Br J Pharmacol       Date:  2001-04       Impact factor: 8.739

6.  Urotensin-II induces ear flushing in rats.

Authors:  J-s Qi; R Schulingkamp; T J Parry; R Colburn; D Stone; B Haertlein; L K Minor; P Andrade-Gordon; B P Damiano
Journal:  Br J Pharmacol       Date:  2007-01-08       Impact factor: 8.739

7.  Photolabelling the urotensin II receptor reveals distinct agonist- and partial-agonist-binding sites.

Authors:  Brian J Holleran; Marie-Eve Beaulieu; Christophe D Proulx; Pierre Lavigne; Emanuel Escher; Richard Leduc
Journal:  Biochem J       Date:  2007-02-15       Impact factor: 3.857

Review 8.  The role of urotensin II in cardiovascular and renal physiology and diseases.

Authors:  Yi-Chun Zhu; Yi-Zhun Zhu; Philip Keith Moore
Journal:  Br J Pharmacol       Date:  2006-06-19       Impact factor: 8.739

Review 9.  Is urotensin-II the new endothelin?

Authors:  Janet J Maguire; Anthony P Davenport
Journal:  Br J Pharmacol       Date:  2002-11       Impact factor: 8.739

10.  Bolus injection of human UII in conscious rats evokes a biphasic haemodynamic response.

Authors:  Sheila M Gardiner; Julie E March; Philip A Kemp; Terence Bennett
Journal:  Br J Pharmacol       Date:  2004-08-31       Impact factor: 8.739
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.