Literature DB >> 10940049

Substrate ambiguity of 3-deoxy-D-manno-octulosonate 8-phosphate synthase from Neisseria gonorrhoeae revisited.

G Y Sheflyan1, A K Sundaram, W P Taylor, R W Woodard.   

Abstract

Homogeneous, recombinant 3-deoxy-D-manno-octulosonate 8-phosphate synthase from Neisseria gonorrhoeae is shown to catalyze the formation of 3-deoxy-D-manno-octulosonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate as determined from (1)H-nuclear magnetic resonance analysis of the product. This enzyme does not catalyze the condensation of D-erythrose 4-phosphate and phosphoenolpyruvate to form 3-deoxy-D-ribo-heptulosonate 7-phosphate, as was previously reported (P. S. Subramaniam, G. Xie, T. Xia, and R. A. Jensen, J. Bacteriol. 180:119-127, 1998).

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Year:  2000        PMID： 10940049      PMCID： PMC111385          DOI： 10.1128/JB.182.17.5005-5008.2000

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  15 in total

1.  Methods for the quantitative estimation of N-acetylneuraminic acid and their application to hydrolysates of sialomucoids.

Authors:  D AMINOFF
Journal:  Biochem J       Date:  1961-11       Impact factor: 3.857

2.  Stereospecificity of the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase reaction.

Authors:  D K Onderka; H G Floss
Journal:  Biochem Biophys Res Commun       Date:  1969-06-27       Impact factor: 3.575

3.  Automated test systems for the determination of deoxy sugars and 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase.

Authors:  G M Rothe; W Maurer; E Bohrisch; P Reichert
Journal:  Anal Biochem       Date:  1980-07-15       Impact factor: 3.365

4.  Identification of essential histidine residues in 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase: analysis by chemical modification with diethyl pyrocarbonate and site-directed mutagenesis.

Authors:  G Y Sheflyan; H S Duewel; G Chen; R W Woodard
Journal:  Biochemistry       Date:  1999-10-26       Impact factor: 3.162

5.  Probing the stereochemistry of E. coli 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (phenylalanine-sensitive)-catalyzed synthesis of KDO 8-P analogues.

Authors:  A K Sundaram; R W Woodard
Journal:  J Org Chem       Date:  2000-09-22       Impact factor: 4.354

6.  Mechanistic studies of 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase from Escherichia coli.

Authors:  A Kohen; A Jakob; T Baasov
Journal:  Eur J Biochem       Date:  1992-09-01

7.  Steric course of the chorismate synthetase reaction and the 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthetase reaction.

Authors:  D K Onderka; H G Floss
Journal:  J Am Chem Soc       Date:  1969-10-08       Impact factor: 15.419

8.  Purification and characterization of 3-deoxy-D-manno-octulosonate 8-phosphate synthetase from Escherichia coli.

Authors:  P H Ray
Journal:  J Bacteriol       Date:  1980-02       Impact factor: 3.490

9.  Essential cysteines in 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase from Escherichia coli: analysis by chemical modification and site-directed mutagenesis.

Authors:  H M Salleh; M A Patel; R W Woodard
Journal:  Biochemistry       Date:  1996-07-09       Impact factor: 3.162

10.  Stereochemistry of 3-deoxyoctulosonate 8-phosphate synthase.

Authors:  G D Dotson; P Nanjappan; M D Reily; R W Woodard
Journal:  Biochemistry       Date:  1993-11-23       Impact factor: 3.162
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  4 in total

1.  The correct phylogenetic relationship of KdsA (3-deoxy-d-manno-octulosonate 8-phosphate synthase) with one of two independently evolved classes of AroA (3-deoxy-d-arabino-heptulosonate 7-phosphate synthase).

Authors:  Roy A Jensen; Gary Xie; David H Calhoun; Carol A Bonner
Journal:  J Mol Evol       Date:  2002-03       Impact factor: 2.395

2.  Identification of a d-Arabinose-5-Phosphate Isomerase in the Gram-Positive Clostridium tetani.

Authors:  David L Cech; Katherine Markin; Ronald W Woodard
Journal:  J Bacteriol       Date:  2017-08-08       Impact factor: 3.490

3.  Functional and biochemical characterization of a recombinant Arabidopsis thaliana 3-deoxy-D-manno-octulosonate 8-phosphate synthase.

Authors:  Jing Wu; Mayur A Patel; Appavu K Sundaram; Ronald W Woodard
Journal:  Biochem J       Date:  2004-07-01       Impact factor: 3.857

4.  Analysis of the arabinose-5-phosphate isomerase of Bacteroides fragilis provides insight into regulation of single-domain arabinose phosphate isomerases.

Authors:  David Cech; Pan Fen Wang; Tod P Holler; Ronald W Woodard
Journal:  J Bacteriol       Date:  2014-06-02       Impact factor: 3.490
  4 in total

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