Literature DB >> 10934524

Generation of stable recombinant retroviruses containing the beta-globin genes linked to complex regulatory elements by using transient transfection.

B Li1, D Liu, J Wang, W Dong, C C Liang.   

Abstract

A transient packaging method for a retroviral vector containing beta-globin sequences, mediated by Ca3(PO4)2 precipitation, generated stable recombinant beta-globin retroviruses with intact viral genomes. We suggest the use of this method as an alternative means to overcome the production of beta-globin encoding retroviruses with aberrant viral genomes using the routine packaging procedure.

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Year:  1999        PMID： 10934524     DOI： 10.1385/MB:13:1:73

Source DB:  PubMed          Journal:  Mol Biotechnol        ISSN： 1073-6085            Impact factor:   2.695


  10 in total

Review 1.  Recent developments in gene therapy for oncology and hematology.

Authors:  M A Roskrow; B Gänsbacher
Journal:  Crit Rev Oncol Hematol       Date:  1998-09       Impact factor: 6.312

2.  Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids.

Authors:  W C Forrester; S Takegawa; T Papayannopoulou; G Stamatoyannopoulos; M Groudine
Journal:  Nucleic Acids Res       Date:  1987-12-23       Impact factor: 16.971

3.  A developmentally stable chromatin structure in the human beta-globin gene cluster.

Authors:  W C Forrester; C Thompson; J T Elder; M Groudine
Journal:  Proc Natl Acad Sci U S A       Date:  1986-03       Impact factor: 11.205

4.  A dominant control region from the human beta-globin locus conferring integration site-independent gene expression.

Authors:  D Talbot; P Collis; M Antoniou; M Vidal; F Grosveld; D R Greaves
Journal:  Nature       Date:  1989-03-23       Impact factor: 49.962

5.  Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene.

Authors:  M Sadelain; C H Wang; M Antoniou; F Grosveld; R C Mulligan
Journal:  Proc Natl Acad Sci U S A       Date:  1995-07-18       Impact factor: 11.205

6.  Community control of hereditary anaemias: memorandum from a WHO meeting.

Authors: 
Journal:  Bull World Health Organ       Date:  1983       Impact factor: 9.408

7.  Factors affecting retroviral vector function and structural integrity.

Authors:  J R McLachlin; N Mittereder; M B Daucher; M Kadan; M A Eglitis
Journal:  Virology       Date:  1993-07       Impact factor: 3.616

8.  High-level beta-globin expression after retroviral transfer of locus activation region-containing human beta-globin gene derivatives into murine erythroleukemia cells.

Authors:  U Novak; E A Harris; W Forrester; M Groudine; R Gelinas
Journal:  Proc Natl Acad Sci U S A       Date:  1990-05       Impact factor: 11.205

9.  A human beta-globin gene fused to the human beta-globin locus control region is expressed at high levels in erythroid cells of mice engrafted with retrovirus-transduced hematopoietic stem cells.

Authors:  I Plavec; T Papayannopoulou; C Maury; F Meyer
Journal:  Blood       Date:  1993-03-01       Impact factor: 22.113

10.  Position-independent, high-level expression of the human beta-globin gene in transgenic mice.

Authors:  F Grosveld; G B van Assendelft; D R Greaves; G Kollias
Journal:  Cell       Date:  1987-12-24       Impact factor: 41.582
  10 in total
  1 in total

1.  Evaluation of optimal expression cassette in retrovirus vector for beta-thalassemia gene therapy.

Authors:  Wen-Ji Dong; Bin Li; De-Pei Liu; Zhen-Xiang Zu; Jia Li; De-Long Hao; Guang Liu; Zhi-Chen Guo; Chih-Chuan Liang
Journal:  Mol Biotechnol       Date:  2003-06       Impact factor: 2.695
  1 in total

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