Literature DB >> 10933593

Pre-B and pre-T-cell receptors: conservation of strategies in regulating early lymphocyte development.

S A Muljo1, M S Schlissel.   

Abstract

Early lymphocyte development is characterized by the regulated activity of the V(D)J recombinase and the positive and negative selection of cells based on the structure of their assembled antigen receptor genes. Developing B and T cells use remarkably similar signaling complexes, the pre-B-cell receptor (pre-BCR) and the pre-T-cell receptor (pre-TCR) respectively, to monitor the progress of antigen receptor gene assembly This review will compare and contrast the regulation and activities of the pre-BCR and pre-TCR signaling complexes. In addition, we will consider a number of critical but as yet unanswered questions prompted by such an analysis.

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Year:  2000        PMID： 10933593

Source DB:  PubMed          Journal:  Immunol Rev        ISSN： 0105-2896            Impact factor:   12.988


  9 in total

1.  Multiple T-cell clones specific for the same foreign pMHC ligand can be generated from a single, ancestral TCR-VDJbeta precursor.

Authors:  Janet L Maryanski; Anne Aublin; Valérie Attuil-Audenis; Abdelbasset Hamrouni
Journal:  Immunol Res       Date:  2004       Impact factor: 2.829

2.  The Ets-1 transcription factor is required for complete pre-T cell receptor function and allelic exclusion at the T cell receptor beta locus.

Authors:  Stéphanie Eyquem; Karine Chemin; Magali Fasseu; Jean-Christophe Bories
Journal:  Proc Natl Acad Sci U S A       Date:  2004-10-20       Impact factor: 11.205

3.  IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development.

Authors:  Runqing Lu; Kay L Medina; David W Lancki; Harinder Singh
Journal:  Genes Dev       Date:  2003-06-27       Impact factor: 11.361

4.  S1P3 confers differential S1P-induced migration by autoreactive and non-autoreactive immature B cells and is required for normal B-cell development.

Authors:  Erin E Donovan; Roberta Pelanda; Raul M Torres
Journal:  Eur J Immunol       Date:  2010-03       Impact factor: 5.532

5.  T cell receptor gene rearrangement lineage analysis reveals clues for the origin of highly restricted antigen-specific repertoires.

Authors:  Abdelbasset Hamrouni; Anne Aublin; Philippe Guillaume; Janet L Maryanski
Journal:  J Exp Med       Date:  2003-03-03       Impact factor: 14.307

6.  DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3.

Authors:  Benjamin J Thompson; Rahul Bhansali; Lauren Diebold; Daniel E Cook; Lindsay Stolzenburg; Anne-Sophie Casagrande; Thierry Besson; Bertrand Leblond; Laurent Désiré; Sébastien Malinge; John D Crispino
Journal:  J Exp Med       Date:  2015-05-25       Impact factor: 14.307

7.  Defined alphabeta T cell receptors with distinct ligand specificities do not require those ligands to signal double negative thymocyte differentiation.

Authors:  Batu Erman; Terry I Guinter; Alfred Singer
Journal:  J Exp Med       Date:  2004-06-21       Impact factor: 14.307

8.  The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling.

Authors:  Thijs J Hagenbeek; Marianne Naspetti; Fabrice Malergue; Fabien Garçon; Jacques A Nunès; Kitty B J M Cleutjens; Jan Trapman; Paul Krimpenfort; Hergen Spits
Journal:  J Exp Med       Date:  2004-09-27       Impact factor: 14.307

Review 9.  The Evolution of Rag Gene Enhancers and Transcription Factor E and Id Proteins in the Adaptive Immune System.

Authors:  Genki Yoshikawa; Kazuko Miyazaki; Hiroyuki Ogata; Masaki Miyazaki
Journal:  Int J Mol Sci       Date:  2021-05-31       Impact factor: 5.923
  9 in total

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