Literature DB >> 10933534

Photodegradation kinetic study and stability-indicating assay of danazol using high-performance liquid chromatography.

E A Kariem1, M A Abounassif, M E Hagga, H A Al-Khamees.   

Abstract

A selective high-performance liquid chromatographic procedure for the stability-indicating determination of danazol in the presence of its photolytic degradation products is demonstrated. The photolysis was carried out in glass vials and quartz cell under UV light at 254 nm. Satisfactory results were obtained for the assay and recovery testing with RSD values less than 2%. Kinetic parameters evaluated comprise the order of reaction and the rate constants of the degradation of the danazol irradiated in glass vials or quartz cell.

Entities:  

Mesh:

Substances:

Year:  2000        PMID: 10933534     DOI: 10.1016/s0731-7085(00)00315-0

Source DB:  PubMed          Journal:  J Pharm Biomed Anal        ISSN: 0731-7085            Impact factor:   3.935


  3 in total

1.  Characterization of Supersaturated Danazol Solutions - Impact of Polymers on Solution Properties and Phase Transitions.

Authors:  Matthew J Jackson; Umesh S Kestur; Munir A Hussain; Lynne S Taylor
Journal:  Pharm Res       Date:  2016-02-18       Impact factor: 4.200

2.  Lipid-based formulations for danazol containing a digestible surfactant, Labrafil M2125CS: in vivo bioavailability and dynamic in vitro lipolysis.

Authors:  Anne Larsen; René Holm; Mette Lund Pedersen; Anette Müllertz
Journal:  Pharm Res       Date:  2008-07-01       Impact factor: 4.200

3.  A new spectrophotometric method for the determination of methyldopa.

Authors:  E A Gadkariem; K E E Ibrahim; N A A Kamil; M E M Haga; H A El-Obeid
Journal:  Saudi Pharm J       Date:  2009-11-10       Impact factor: 4.330

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.