Control of action as mediated by the human frontal lobe.

Conscious control of action involves the voluntary initiation and the continuous adjustment of motor activity. Neuroimaging data provide evidence that the plan for a movement is developed with respect to the behavioral context in prefrontal cortex, while the synergies of a motor program are coded by premotor cortex and the specific movement parameters by the motor cortex. It is suggested that the initiational aspects of conscious motor activity are implemented in a medial system of information flow and the integrative aspects in a lateral system of the human frontal lobe.